April 2017 in “Journal of Dermatological Science” In this study, both 2.5% benzoyl peroxide gel and 0.1% adapalene gel exhibited comedolytic effects on the spontaneous comedogenic rhino mouse model.
2 citations
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June 1989 in “Archives of Dermatology” This case report describes a 65-year-old man's trichofolliculoma, a hair follicle-origin tumor, which appeared as a persistent cheek pore extrusion and was removed at the patient's request.
January 2026 in “Indian Journal of Paediatric Dermatology” In this case report, a 14-year-old boy was diagnosed with nevus comedonicus, a condition characterized by dilated follicular openings filled with keratin, presenting in a Blaschkoid pattern; treatment with topical tretinoin 0.1% cream was recommended.
February 2025 in “Pharmaceuticals” This study found that supplementing myo-inositol with microlipodispersed magnesium significantly improved acne and hirsutism in women with PCOS by reducing BMI, testosterone, and DHEAS levels, also enhancing quality of life without side effects, over 6 months.
July 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” This review explores the potential of microneedling as a drug delivery system for treating melasma, focusing on its mechanisms, safety, efficacy, and clinical advantages over conventional therapies like hydroquinone and lasers.
May 2020 in “International journal of dermatology and venereology” This study introduces the term "hair matrix cyst" for a cyst with both pilomatricoma and epidermal cyst characteristics, highlighting its potential for misdiagnosis among similar skin conditions.
22 citations
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September 2019 in “Trends in Immunology” This paper proposes that acne vulgaris is a transient inflammatory response during adolescence due to changes in facial skin's microbiota and sebum environment rather than a stable skin condition.
In this case report, a woman's Majocchi's granuloma, linked to her pet guinea pig infected with Trichophyton mentagrophytes, improved significantly with a combination of terbinafine and ketoconazole cream.
2 citations
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January 2022 in “Actas Dermo-Sifiliográficas” In this study, researchers found that dermoscopy revealed specific features in Malassezia folliculitis, such as folliculocentricity and perilesional erythema, which can aid in its identification and potentially distinguish it from acne vulgaris.
172 citations
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December 2004 in “Journal of The American Academy of Dermatology” In this study, demodicoses were found to be relatively common among immunocompetent patients, with a notable overlap with papulopustular rosacea.
27 citations
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July 2017 in “European Journal of Dermatology” This article reviews the role of microRNAs as epigenetic modulators in dermatology but reports no new clinical findings.
January 2008 in “OhioLink ETD Center (Ohio Library and Information Network)” This review explores the potential of targeted topical drug delivery to hair follicles for treating conditions like acne and hair loss but reports no clinical results, emphasizing the need for more research.
3 citations
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November 2017 in “International Journal of Pharmacy and Pharmaceutical Sciences” This study identified new oxidative derivatives of finasteride, including a newly discovered metabolite, by using the fungus Macrophomina phaseolina.
81 citations
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February 2014 in “Clinics in dermatology” This review discusses the potential role of Demodex mites in various human skin conditions, including acneiform eruptions and folliculitis, but reports no new research findings.
35 citations
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March 2012 in “Journal of dermatological science” This observational study aims to more accurately detect and localize Propionibacterium acnes in acne lesions by combining multiple microbiological visualization techniques, but it does not present new results on their causality to acne.
In this study assessing post-menopausal Asian women, distinct shifts in Malassezia species prevalence on the skin were linked to increased inflammation and impaired skin barrier function, potentially driving disorders like psoriasis and seborrheic dermatitis.
July 2021 in “Journal of dermatology research and therapy” This article discusses the mechanisms by which Cutibacterium acnes contributes to acne vulgaris and mentions potential triggers like UV light and tobacco, but it reports no new clinical results.
January 2019 in “FarFar - Pharmacy Repository” This article reviews strategies like microemulsions to improve adapalene delivery in acne treatment but reports no new clinical results.
26 citations
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May 2019 in “PLOS ONE” This study observed that hair follicles in hair loss patients had increased levels of Propionibacterium acnes, potentially linked to elevated immune response gene expression in miniaturized hair follicles.
January 2026 in “Drug Delivery and Translational Research” This study investigated the integration of crystal engineering and microneedle technology for androgenetic alopecia treatment, finding that microneedles loaded with newly developed Kopexil multicomponent crystals reduced drug diffusion rates in vitro compared to standard formulations.
January 2025 in “Dermatology Research and Practice” This study examines how skin microbiota and the gut-skin axis affect acne development, aiming to reveal mechanisms that could inform future treatment strategies for acne and other inflammatory skin conditions.
1 citations
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November 2021 in “Biomedicines” This review elaborates on the concept of cutaneous mosaicism and its link to acneiform conditions, but it reports no new clinical results.
1 citations
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January 2026 This study reveals that the microRNA-200 family, highly enriched in hair matrix progenitors, restricts sebaceous gland development by inhibiting the SOX9-dependent lipogenic program, highlighting its specific role in epithelial plasticity within hair follicles.
25 citations
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June 2015 in “Clinical, Cosmetic and Investigational Dermatology” This study found that using an electrical microneedling device enhanced the penetration of liposomal melanin-fluorescein into hair structures and widened the follicular infundibulum in ex vivo human skin models.
1 citations
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November 2016 in “Experimental and Therapeutic Medicine” In this study using guinea pigs, the low-dose 800 nm semiconductor laser was found to effectively treat skin blackheads and coarse pores by promoting hair follicle cell apoptosis, while maintaining PCNA expression levels in sebaceous glands.
July 2026 in “Journal of the European Academy of Dermatology and Venereology” January 2015 in “프로그램북(구 초록집)” This study highlights that the combination of adapalene and benzoyl peroxide (Epiduo®) is an effective first-line treatment for acne, significantly inhibiting antibiotic-susceptible and antibiotic-resistant P. acnes strains.
50 citations
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December 2017 in “Nanoscale” This study found that polymeric micelle formulations significantly improved the targeted delivery of adapalene to hair follicles compared to standard Differin® products, which suggests potential advantages in treating hair follicle-related conditions and reducing side effects.
1 citations
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July 2023 in “Clinical Cosmetic and Investigational Dermatology” In this report, a 54-year-old woman with familial dyskeratotic comedones showed slight improvement in skin lesions after topical retinoids and urea cream. This source also describes the first dermoscopic findings for this condition and reviews 21 previous cases.
1 citations
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January 2009 In this case report, a 25-year-old man with nevus comedonicus showed no improvement from keratolytics and topical tretinoin, but had success with surgical excision of the lesions.