Familial Dyskeratotic Comedones: A Case Report and Literature Review

    July 2023 in “ Clinical Cosmetic and Investigational Dermatology ”
    Kasama Tejapira, Poonkiat Suchonwanit
    TLDR Familial dyskeratotic comedones are a rare, benign skin disorder that is hard to treat.
    This case report and literature review focus on familial dyskeratotic comedones (FDC), a rare autosomal dominant skin condition. It highlights a 54-year-old Thai woman with FDC since age 12, emphasizing the condition's benign and asymptomatic nature, which often leads to underdiagnosis. The study reviews 21 cases from 11 families, stressing the importance of recognizing FDC's clinical and histological features for accurate diagnosis. Despite its rarity, FDC is resistant to treatment, with limited therapeutic options. The report also introduces new dermoscopic features to aid in differentiating FDC from similar conditions.
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