March 2021 in “Actas Dermo-Sifiliográficas” This review discusses the scalp microbiome's unique features and its potential role in hair disorders, suggesting that microbiome-targeted treatments could offer new therapeutic options, though no clinical results are reported.
July 2026 in “Journal of Investigative Dermatology” This study found that omega-6 and saturated fatty acid-enriched diets promote weight gain and certain skin changes regardless of gut microbiota, while omega-3 diets limit adiposity and affect skin in a microbiota-dependent way in mice, highlighting a diet–microbiota–lipid relationship in skin health.
June 2026 in “Frontiers in Allergy” In this study, patients with scalp seborrheic dermatitis exhibited distinct patterns of allergen sensitization tied to symptoms, impaired skin barrier, and altered microbiota, emphasizing the need to consider allergen exposure, barrier status, and microbial balance when interpreting patch test results.
March 2026 in “Current Topics in Medicinal Chemistry” This review found that gut microbiota and exosomal microRNAs may collectively impact androgenetic alopecia progression by modulating immune responses and intercellular communication, suggesting new therapeutic possibilities; however, further research is needed to clarify these mechanisms.
February 2026 in “Frontiers in Microbiology” This review examines current understanding of how skin microbiota interact with and influence wound healing, highlighting the roles of commensal microorganisms in inflammation resolution, tissue regeneration, and barrier restoration, and discusses potential microbiota-based therapies for improving wound management.
This study observed that in young women, the scalp microbiota is influenced by sebum level, barrier sensitivity, and lifestyle factors, with barrier sensitivity emerging as a key factor, offering insights for further research into scalp health and conditions.
January 2026 in “The American Journal of Medical Sciences and Pharmaceutical Research” This study reports that disruptions to the scalp microbiome from invasive cosmetic procedures may contribute to dermatological conditions, and suggests incorporating microbiome assessments and personalized restoration programs into trichological and dermatological practices.
December 2025 in “Cosmetics” This research identified unique gut microbiota patterns in alopecia areata patients, with potential as diagnostic biomarkers and suggesting avenues for microbiota-focused therapies.
October 2025 in “Progress In Microbes & Molecular Biology” This review reveals that PCOS is consistently linked to gut microbiota dysbiosis, characterized by reduced microbial diversity and shifts in composition, which are associated with various PCOS phenotypes and may present opportunities for microbiota-targeted therapies addressing the disorder's underlying pathophysiological mechanisms.
October 2025 in “Scientia Generalis” In this narrative review, dysbiosis was found to potentially influence androgen metabolism and immune response, suggesting that gut microbiota balance may play a role in the prevention and treatment of androgenetic and areata alopecia.
July 2025 in “BMC Microbiology” This study observed that pancreatic cancer-related skin lesions in mice are linked to microbiota imbalances, specifically noting changes in the abundance of certain bacterial genera, which may offer potential diagnostic or therapeutic targets for managing skin complications in humans with pancreatic cancer.
January 2025 in “Universidad de Córdoba Insitutional Repository (Universidad de Córdoba)” In this study, researchers observed that individuals with alopecia areata exhibited significant changes in scalp microbiota diversity and composition, which were linked to disease severity and inflammation markers, though it remains unclear if these microbial shifts are a cause or a result of hair loss.
September 2023 in “Current opinion in microbiology” This source discusses how the skin mycobiome, dominated by Malassezia fungi, may provide a unique niche that can be disrupted by environmental changes, potentially leading to the fungal pathogen C. auris overtaking Malassezia and predisposing individuals to severe infections.
January 2023 in “Discovery immunology” T cells and bacteria in the gut and skin help maintain health and protect against disease.
2 citations
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June 2022 in “The Bulletin of Contemporary Clinical Medicine” This study suggests that although hydroxyapatite gel has strong bactericidal effects, its combination with platelet-enriched blood autoplasm does not enhance antibacterial activity in endodontic treatment for chronic apical periodontitis.
1 citations
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April 2023 in “Biomolecules” This study found that hair care products containing fermented papaya, fermented mangosteen, and caffeine significantly inhibited hair loss, increased hair density and thickness, and improved hair follicle structure in individuals with androgenic or diffuse alopecia over three months compared to placebo and caffeine controls.
June 2026 in “Frontiers in Physiology” In this study, a topical cream containing 3% lactic acid ferment lysate (VHProbi ® MixP) was found to significantly reduce sebum, porphyrin levels, and pore size, while increasing hydration and improving skin texture in participants with oily skin over a 60-day period.
134 citations
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January 2019 in “American journal of clinical dermatology” This review summarizes recent research on the skin microbiome's role in acne development and how antibiotic treatments affect skin microbes, but it reports no new clinical results.
65 citations
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October 2018 in “Frontiers in cellular and infection microbiology” This study observed that dandruff in Indian women is associated with a distinct scalp microbiome, including specific bacterial and unknown Malassezia species, with implications for nutrient homeostasis and cell-host adhesion pathways.
47 citations
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March 2022 in “Frontiers in cellular and infection microbiology” This review discusses the role of the skin microbiome in the pathogenesis of various skin disorders, such as atopic dermatitis and psoriasis, and reports no new clinical findings; it emphasizes potential therapeutic implications.
40 citations
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September 2019 in “World journal of clinical cases” In this case report, an 86-year-old man experienced new hair growth and color change in alopecia areata after receiving fecal microbiota transplantation for noninfectious diarrhea.
37 citations
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September 2018 in “Psychoneuroendocrinology” This study found that finasteride treatment in male rats led to enduring effects on depressive-like behavior, hippocampal neurogenesis and neuroinflammation, and gut microbiota composition after withdrawal.
18 citations
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September 2023 in “Experimental Dermatology” This review examines the role of skin microbes in enhancing the skin barrier and their involvement in skin diseases like atopic dermatitis, while also discussing current and future therapeutic strategies targeting the skin microbiome.
18 citations
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August 2019 in “Nutrients” In this study, lifelong barley intake in SAMP8 mice was associated with extended lifespan, improved aging-related phenotypes, and beneficial shifts in the intestinal microbiome.
17 citations
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September 2020 in “Journal of Endocrinological Investigation” This study found that the gut microbiota composition in patients with post-finasteride syndrome differs significantly from healthy controls, with reduced diversity and specific microbial changes, suggesting a potential diagnostic marker and therapeutic target.
16 citations
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January 2021 in “Dermatology and therapy” This review discusses the role of gut microbiota in autoimmune and immune-mediated dermatological conditions like lupus and psoriasis, but reports no new clinical results; the authors emphasize the need for further study into microbial signatures and treatments.
15 citations
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April 2020 in “Intestinal Research” This study observed that fecal microbiota transplantation for ulcerative colitis may also offer incidental benefits such as weight loss, improved hair loss, and relief from axial arthritis and allergic rhinitis.
13 citations
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January 2022 in “Advances in Dermatology and Allergology” This review discusses the relationship between gut microbiota and alopecia areata, and it does not report new clinical results.
11 citations
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October 2024 in “International Journal of Molecular Sciences” This study observed that the cutaneous microbiome in psoriasis patients differs both qualitatively and quantitatively from healthy individuals, suggesting a potential link to psoriasis pathogenesis.
11 citations
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November 2021 in “International journal of molecular sciences” In this study, germ-free male mice showed altered levels of certain neuroactive steroids in the brain and periphery, suggesting microbiota may influence neuroendocrine pathways that support brain functioning.