Gut Microbiota in Alopecia Areata

January 2022 in “ Advances in Dermatology and Allergology ”

Karolina Brzychcy, Izabela Dróźdż, Sebastian Skoczylas, Tomasz Płoszaj, Dorota Sobolewska-Sztychny, Małgorzata Skibińska, Joanna Narbutt, Aleksandra Lesiak

alopecia areata gut microbiota Firmicutes Proteobacteria Bacteroidetes microbial richness microbial diversity AA

The study "Gut microbiota in alopecia areata" examines the gut microbiome of 25 patients with alopecia areata (AA) and finds a disturbed microflora characterized by an overrepresentation of Firmicutes and Proteobacteria, and a reduction in Bacteroidetes, leading to a higher Firmicutes to Bacteroidetes ratio. This pattern is similar to that seen in other conditions like obesity and inflammatory bowel disease. The study also notes a loss of microbial richness and diversity in AA patients. These findings suggest a potential link between gut microbiota disturbances and AA, highlighting the need for further research to understand this relationship and its implications for treatment.

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