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Treatment of Male Rats with Finasteride, an Inhibitor of 5alpha-Reductase Enzyme, Induces Long-Lasting Effects on Depressive-Like Behavior, Hippocampal Neurogenesis, Neuroinflammation, and Gut Microbiota Composition

research Treatment of Male Rats with Finasteride, an Inhibitor of 5alpha-Reductase Enzyme, Induces Long-Lasting Effects on Depressive-Like Behavior, Hippocampal Neurogenesis, Neuroinflammation, and Gut Microbiota Composition

37 citations , September 2018 in “Psychoneuroendocrinology”

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

research Evaluation of the Treatment Effect of Aloe Vera Fermentation in Burn Injury Healing Using a Rat Model

15 citations , January 2019 in “Mediators of inflammation”

Aloe vera fermentation helps heal burns faster by reducing inflammation and changing gut bacteria.

research Gut Microbiota in Alopecia Areata

13 citations , January 2022 in “Advances in Dermatology and Allergology”

Alopecia areata may be linked to imbalanced gut bacteria.

research The Human Skin Microbiome in Selected Cutaneous Diseases

47 citations , March 2022 in “Frontiers in cellular and infection microbiology”

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

research The Role of Gram-Positive Bacteria in Acne Vulgaris

June 2023 in “Benha Journal of Applied Sciences”

Acne is caused by multiple types of bacteria.

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community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 197 upvotes 4 months ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.