Unveiling the Connection Between Gut Microbiome and Polycystic Ovary Syndrome

    October 2025 in “ Progress In Microbes & Molecular Biology ”
    Y. Li, Ke-Yan Loo, Loh Teng‐Hern Tan, Jodi Woan‐Fei Law, Malarvili Selvaraja, Learn−Han Lee, Yatinesh Kumari, Vanassa Ratnasingam, Vengadesh Letchumanan
    TLDR PCOS is linked to gut bacteria changes, suggesting gut-focused treatments might help.
    Polycystic ovary syndrome (PCOS) is linked to gut microbiota dysbiosis, characterized by reduced microbial α-diversity and compositional shifts, which correlate with PCOS symptoms like insulin resistance and chronic inflammation. This review of 25 articles highlights the role of gut microbiome alterations in PCOS pathophysiology, suggesting that microbiota-targeted therapies could address the disorder's underlying mechanisms rather than just its symptoms.
    Discuss this study in the Community →