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Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The study found that in Latin America, ancestry varies by location, influences physical traits, and affects how people perceive their own heritage.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Minoxidil boosts hair growth by increasing cell production and survival.

K6hf is a unique protein found only in a specific layer of hair follicles.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.