Regression of Pathological Changes Induced by Long-Term Administration of Contraceptive Steroids to Rodents

    June 1985 in “ Toxicologic Pathology ”
    George Lumb, Lorelie Mitchell, Felix A. de la Iglesia
    Studysummary In this study, prolonged high-dose steroid treatment in rats caused several pathological changes, some of which regressed, particularly improvements in mammary gland tumors and pituitary-related symptoms, after stopping treatment.
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    Research cited in this study 3

    1. Studies of the Components of an Oral Contraceptive Agent in Albino Rats: Estrogenic Component Journal of Toxicology and Environmental Health · 1980
    2. Studies of the Components of an Oral Contraceptive Agent in Albino Rats: Progestogenic Component and Comparison of Effects of the Components and the Combined Agent Journal of Toxicology and Environmental Health · 1980
    3. Long-Term Toxicologic and Tumorigenesis Studies on an Oral Contraceptive Agent in Albino Rats Toxicology and Applied Pharmacology · 1970