Safe Selection of Genetically Manipulated Human Primary Keratinocytes with Very High Growth Potential Using CD24

August 2007 in “ Molecular Therapy ”

Valérie Bergoglio, Fernando Larcher, Odile Chevallier-Lagente, Alain Bernheim, Olivier Danos, Alain Sarasin, Marcela Del Río, Thierry Magnaldo

keratinocytes CD24 GFP stem cells genetic instability gene transfer carcinogenesis metastasis in vitro in vivo green fluorescent protein gene therapy

Studysummary This study found that using ectopic expression of CD24 is a promising approach for selecting genetically modified human epidermal stem cells for safe cutaneous gene therapy in cancer-prone conditions.

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