24 citations
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April 2016 in “Experimental Dermatology” This study found that chemical treatments like perming, dyeing, and bleaching significantly alter amino acids and lipids in human hair, which may impact hair strength and quality.
2 citations
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June 2024 in “Heliyon” This study identified 1965 different metabolites in various tissues of *Oresitrophe rupifraga* Bunge using a targeted metabolomics approach and found significant metabolic differences between its aboveground and underground parts, providing insights into the plant's unique growth traits and potential cultivation and utilization.
1 citations
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March 2020 in “Functional foods in health and disease/Journal of functional foods in health & disease” This study found that OM-X® supplementation effectively prevented adverse biological changes caused by vitamin C deficiency in SMP30/GNL KO mice, improving energy maintenance, antioxidant capacity, and protein synthesis.
December 2025 in “Frontiers in Veterinary Science” This study found that PT-LCG extends hair follicle activity and promotes continuous cashmere growth by enhancing lipid synthesis, remodeling the extracellular matrix, and modulating inflammatory signaling, offering insights into improving cashmere yield and quality through molecular breeding.
February 2025 in “BMC Genomics” This study found that in cashmere goats, melatonin treatments enhanced cashmere growth by stimulating secondary hair follicles, increasing follicle density, and improving yield and quality, highlighting key genes and metabolic pathways involved in this process.
September 2026 in “Animals” This study found that Rex rabbits had significantly shorter fibre length and thinner fur compared to New Zealand White rabbits, and identified a gene-metabolite network that may influence fur quality and development.
7 citations
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September 2014 in “PubMed” This study observed that androgenetic alopecia is significantly associated with an increased risk of metabolic syndrome, with notable correlations found among both male and female subjects across European and Asian populations.
48 citations
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January 2018 in “Scientific Reports” This pilot study found that hair metabolome analysis may help differentiate pregnancy complications from healthy pregnancies by revealing significant metabolite differences between trimesters.
22 citations
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January 2019 in “Hormone and Metabolic Research” This meta-analysis confirmed associations between some androgenic and metabolic parameters in women with PCOS, suggesting that these measurements might help predict metabolic risk in this population.
13 citations
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September 2022 in “Biomolecules” This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.
3 citations
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December 2021 in “Acta dermato-venereologica” This meta-analysis found that patients with androgenetic alopecia had a significantly higher prevalence of metabolic syndrome and poorer metabolic profiles compared to controls, especially among females, those with early onset, and individuals of African ethnicity.
2 citations
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September 2023 in “Health science reports” This meta-analysis found a strong association between metabolic syndrome and certain skin diseases, including psoriasis, hidradenitis suppurativa, androgenetic alopecia, and lichen planus, suggesting increased risk compared to the general population.
4 citations
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February 2022 in “Frontiers in molecular biosciences” This study revealed that chronic restraint stress in mice led to significant alterations in metabolic pathways and gene expression associated with hair growth inhibition, using metabolomics and transcriptomics analyses.
May 2023 in “Research Square (Research Square)” This study identified 18 significant metabolites and two enriched metabolic pathways, necroptosis and ABC transporters, in serum samples of acne patients with and without insulin resistance, potentially aiding in the clinical diagnosis and drug development for these patients.
137 citations
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April 2001 in “Journal of Clinical Investigation” This study found that alopecia in VDR-null mice persists despite undetectable vitamin D levels, indicating a defect in epithelial-mesenchymal communication due to the absence of ligand-independent receptor function.
19 citations
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March 2021 in “Obesity surgery” This study found that hair loss is common following metabolic and bariatric surgery, particularly among younger women with low serum levels of zinc, folic acid, and ferritin.
2 citations
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October 2017 in “PubMed” This study found that serum bone metabolic markers with mild changes are interdependently related to traditional Chinese medicine syndromes in patients with chronic kidney disease-related bone disorders.
January 2022 in “Surgical and Cosmetic Dermatology” This study found a significant correlation between androgenic alopecia and metabolic syndrome, suggesting individuals with alopecia have higher odds of metabolic syndrome.
January 2026 in “RSC Advances” This study used a zebrafish model and advanced mass spectrometry to identify 11 metabolites of epristeride, revealing significant effects on purine metabolism and aromatic amino acid biosynthesis, which may aid in developing anti-doping detection methods.
October 2023 in “Journal of the Endocrine Society” In this study, distinct androgen excess subtypes were identified in women with PCOS, with the adrenal androgen excess cluster showing significantly higher rates of insulin resistance and type 2 diabetes, suggesting 11-oxygenated androgens as potential drivers of metabolic risk.
January 2017 in “The Journal of Korean Medicine Ophthalmology&Otorhinolaryngology&Dermatology” This study found that early-onset male androgenetic alopecia is significantly associated with an increased risk of metabolic syndrome.
7 citations
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September 2024 in “Scientific Reports” This study suggests that sebum samples can be effectively stored and transported with less stringent requirements than liquid samples, making them suitable for remote or at-home collection before clinical analysis.
This study found significant differences in cashmere fiber diameters between two groups of cashmere goats and identified 211 genes and 50 metabolites related to hair follicle growth and cellular functions, suggesting potential pathways to improve cashmere quality.
3 citations
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May 2023 in “Endocrine Abstracts” This study identified three subgroups of women with PCOS with distinct androgen profiles, finding that the subgroup with adrenal-derived androgen excess had the highest insulin resistance and rates of hirsutism and hair loss.
28 citations
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February 2023 in “Healthcare” This study found a notably high prevalence of metabolic syndrome among apparently healthy individuals in Pakistan, with high triglycerides, low HDL, and central obesity identified as significant risk factors.
59 citations
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July 2023 in “PLoS ONE” This study reveals a high prevalence of multiple sclerosis in Africa, indicating an epidemiological shift in the region and underscoring the need for early prevention and treatment strategies.
This article reviews the potential link between male androgenetic alopecia and metabolic syndrome, noting the lack of conclusive evidence establishing an association.
4 citations
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December 2023 in “Clinical Cosmetic and Investigational Dermatology” This study found that in people with leprosy sequelae, ulcers on the lower limbs exhibited decreased microbial diversity and reduced abundance of specific bacteria compared to normal skin, with skin metabolites closely linked to these microbial changes.
70 citations
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February 2009 in “Biological Trace Element Research” 1 citations
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April 2019 in “Acta medica Philippina” This study found that androgenetic alopecia is significantly associated with an increased risk of Metabolic Syndrome, particularly in early-onset male cases and females exhibiting severe AGA.