Machine Learning-Based Steroid Metabolome Analysis in Women With Polycystic Ovary Syndrome Reveals Three Distinct Androgen Excess Subtypes With Different Metabolic Risk Profiles

    October 2023 in “ Journal of the Endocrine Society ”
    Thaís Rocha, Eka Melson, Roland J. Veen, Lida Abdi, Tara McDonnell, Veronika Tandl, James Hawley, Laura B. L. Wittemans, Amarah Anthony, Lorna Gilligan, Fozia Shaheen, Punith Kempegowda, Caroline D. T. Gillett, Leanne Cussen, Cornelia Missbrenner, Fannie Lajeunesse-Trempe, Helena Gleeson, Aled Rees, Lauren Robinson, Channa Jayasenna, Harpal S. Randeva, Harpal S. Randeva, Georgios K. Dimitriadis, Larissa Gomes, Alice Sitch, Eleni Vradi, Angela E. Taylor, Michael O’Reilly, Barbara Obermayer‐Pietsch, Michael Biehl, Wiebke Arlt
    Image of study
    TLDR Machine learning identified three unique subtypes of androgen excess in women with PCOS, each with different metabolic risks.

    We don't know much about this study yet.

    We're maintaining the world's largest resposity of hair loss research. You can help out the community by sending a PDF of this study here . Not sure how to get a study's PDF? You can email the authors of the study.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 613 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 11 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community My hair after 3 steroid cycles

      in Progress Pictures  27 upvotes 1 year ago
      A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 2 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community risks with finasteride and dutasteride

      in Research/Science  138 upvotes 1 week ago
      Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

      community How to Keep Your Hair on Steroids

      in Treatment  25 upvotes 10 months ago
      To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

    Related Research

    1 / 1 results