The study examined the relationship between regulatory factors and cashmere fiber diameter in 400 female Liaoning cashmere goats, divided into coarse and fine hair types. Significant differences in fiber diameters were found between the groups. Transcriptomic analysis identified 211 differentially expressed genes, such as FGF18, KRT36, KRT79, AWAT2, and MOGAT1, linked to hair follicle growth and sebum secretion through PPAR and glycerol–lipid metabolism pathways. Metabolomics analysis identified 50 differentially expressed metabolites involved in cellular ion channels and neurological pathways, including ABC transporter protein pathways and arachidonic acid metabolism. These findings could help improve cashmere quality in goats.
January 2024 in “Biological & pharmaceutical bulletin” Panax ginseng extract helps human hair grow by encouraging growth phase transition and cell proliferation while reducing certain protein expression.
17 citations
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July 2022 in “BMC Genomics” The FA2H gene improves cashmere fineness by enhancing hair growth in goats.
1 citations
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July 2019 in “Small ruminant research” Nerve growth factor helps cashmere goat hair cells grow by activating a specific protein.
12 citations
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September 2018 in “Naturwissenschaften” Melatonin treatment increases a specific RNA in goat cells that boosts cashmere growth.
29 citations
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October 2017 in “Journal of proteomics” The research found specific proteins that affect fiber characteristics and hair growth in sheep and goats.
104 citations
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October 2016 in “PLoS ONE” CRISPR/Cas9 gene editing in cashmere goats increases hair follicles and fiber length, boosting cashmere yield.
1 citations
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July 2016 in “Livestock science” Nerve growth factor helps cashmere goat hair cells grow and is more active during the hair growth phase.
19 citations
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May 2016 in “Cytotechnology”
1 citations
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November 2020 in “Research Square (Research Square)” The study found specific skin cells and genes that may affect the quality of cashmere in Liaoning Cashmere Goats.