research Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells
Allopregnanolone changes gene expression in glioblastoma cells.
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research Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite
Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
research Hormone-Dependent Medial Preoptic, Lumbar Spinal Cord, and Autonomic Coordination Supporting Male Sexual Behaviors
Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
research Urinary Steroids in Women with Androgenic Alopecia
Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.
research Hair Regeneration by Small Molecules That Activate Autophagy
Certain small molecules can help regrow hair by turning on the body's cell cleanup process.
research In Vivo Uptake and Metabolism of Testosterone by the Skin and Other Tissues of the Rat
Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
research Attenuation of 5α-Reductase-Mediated Progesterone Metabolism Promotes Differentiation of Human Endometrial Stromal Cells for the Establishment of Pregnancy
Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.
research Salicylate Ingestion And Idiopathic Hair Loss
Avoiding aspirin may prevent hair loss.
research Aromatase Inhibition by Letrozole Attenuates Kainic Acid-Induced Seizures but Not Neurotoxicity in Mice
Letrozole reduces seizures but not brain damage in mice.
research Stimulation of Hair Growth by Small Molecules That Activate Autophagy
Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.
research Effectiveness of Short-Term Canrenone Treatment in Idiopathic Hirsutism
Canrenone effectively reduced hair growth and testosterone levels in women with excessive hairiness.
research Effect of the 5α-Reductase Enzyme Inhibitor Dutasteride in the Brain of Intact and Parkinsonian Mice
Dutasteride may protect the brain in early Parkinson's disease.
research Epitestosterone: Regulatory Roles in Androgen-Dependent Processes
Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
research Androgenetic Alopecia
Androgenetic alopecia is a common hair loss condition caused by testosterone effects on hair follicles, leading to thinner, shorter, and less pigmented hair, diagnosed using scalp dermoscopy and treated with topical minoxidil, antiandrogen agents, and 5-alpha reductase inhibitors.
research Role of the Soluble Epoxide Hydrolase in Hair Follicle Stem Cell Homeostasis and Hair Growth
The enzyme sEH is important for hair growth and its inhibition could help treat hair loss.
research A Risk-Benefit Assessment of Treatment with Finasteride in Benign Prostatic Hyperplasia
Finasteride helps reduce prostate size and symptoms in BPH but is less effective than terazosin and works best for larger prostates.
research Vanillic Acid Stimulates Anagen Signaling via the PI3K/Akt/β-Catenin Pathway in Dermal Papilla Cells
Vanillic acid from wheat bran may promote hair growth by activating certain cell pathways and reversing hormone-related hair loss.
research The Effect of St. John's Wort on the Pharmacokinetics, Metabolism, and Biliary Excretion of Finasteride and Its Metabolites in Healthy Men
St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.
research Hair Loss and 5-Aminosalicylic Acid Enemas
5-aminosalicylic acid enemas may cause hair loss.
research Finasteride Reduces Total Cholesterol in LDLR-Deficient Mice
High doses of finasteride lower cholesterol and body weight in certain mice.
research Androgens and Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
research Spironolactone
Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.
research Production of Biologically Active Oxidized Derivatives of Finasteride Through Metabolism by Aspergillus Niger Culture
Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.
research Long-Term Treatment with a 5-Alpha-Reductase Inhibitor Alleviates Depression-Like Behavior in Obese Male Rats
Long-term finasteride treatment reduces depression and brain issues in obese male rats.
research Finasteride Inhibits the Progesterone-Induced Spike-Wave Discharges in a Genetic Model of Absence Epilepsy
Finasteride blocks progesterone's effect on absence seizures in rats.
research Tacrolimus in Dermatology
Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.
research Tacrolimus in Dermatology
Tacrolimus is an effective treatment for several skin conditions with fewer side effects than cyclosporine.
research Role of Prolactin in Regulating the Onset of Winter Fur Growth in Mink: A Reconsideration
Prolactin levels do not control the start of winter fur growth in mink.
research A 30-Year-Old Man with Recurrent Scaling and Itching of the Scalp
A man has a common skin condition called seborrheic dermatitis, treated with special shampoos and sometimes medication.