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St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

Hair color and length affect metabolite profiles in hair, so they should be considered in hair analysis.

Hair follicle development in cashmere goats involves dynamic changes in proteins and metabolites, with key roles for oxytocin, MAPK, and Ca2+ pathways.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

The document concludes that finasteride can reduce nandrolone detection in doping tests, suggesting frequent testing and setting metabolite level thresholds for detection.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

Patients with acne and insulin resistance have different blood metabolites compared to those with only acne, which could help in diagnosis and treatment.

Alopecia Areata is linked to specific gut bacteria and metabolites, indicating a complex gut microbiome.

Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.

Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Drugs can be incorporated into hair based on their chemical properties and hair pigmentation.

Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.

Drugs localize differently in hair strands based on their properties.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

Researchers found markers that can tell if hair has been bleached, which could improve hair test accuracy.

Finasteride and analogues separated using LC-MS-MS technique.

New tests detect finasteride and dutasteride in urine quickly and easily.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

LAAM caused developmental toxicity in tolerant rats without causing birth defects.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

The study aims to create a model to predict health attributes using diverse health data from Japanese adults.