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    Glossary Merkel cells

    specialized skin cells that detect touch and pressure

    Merkel cells are specialized skin cells located in the epidermis, particularly in areas with high tactile sensitivity like fingertips. They function as mechanoreceptors, meaning they help detect touch and pressure, and are connected to nerve endings to transmit sensory information to the brain.

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    Research 30 of 739

    1. Merkel Cell Carcinoma: More Deaths but Still No Pathway to Blame Journal of Investigative Dermatology · 2007 · 211 citations
    2. Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection Cell Host & Microbe · 2016 · 133 citations
    3. Dynamics of Merkel Cell Patterns in Developing Hair Follicles in the Dorsal Skin of Mice, Demonstrated by a Monoclonal Antibody to Mouse Keratin 8 Cells Tissues Organs · 1995 · 64 citations
    4. Epithelial skirt and bulge of human facial vellus hair follicles and and associated Merkel cell-nerve complex Archives of Dermatological Research · 1993 · 48 citations
    5. Ectopic<i>Atoh1</i>expression drives Merkel cell production in embryonic, postnatal and adult epidermis Development · 2015 · 41 citations
    6. Merkel cell differentiation in trichoblastoma Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · 1998 · 34 citations
    7. The cellular basis of mechanosensory Merkel-cell innervation during development eLife · 2019 · 32 citations
    8. Localization of Merkel cells at hairless and hairy human skin sites using keratin 18 Biochemistry and Cell Biology · 1995 · 28 citations
    9. Long-term staining of live Merkel cells with FM dyes Cell and Tissue Research · 2003 · 27 citations
    10. Spatial relationship between Merkel cells and Langerhans cells in human hair follicles Journal of dermatological science · 2002 · 27 citations
    11. Merkel Cells in Hyperplastic and Neoplastic Lesions of the Skin Dermatology · 1998 · 24 citations
    12. Multifunctional Merkel cells: Their roles in electromagnetic reception, finger-print formation, Reiki, epigenetic inheritance and hair form Medical hypotheses · 2010 · 23 citations
    13. Merkel cell carcinoma: updates in tumor biology, emerging therapies, and preclinical models Frontiers in Oncology · 2024 · 17 citations
    14. Direct cellular reprogramming enables development of viral T antigen–driven Merkel cell carcinoma in mice 2022 · 14 citations
    15. Localization of the rabies virus antigen in Merkel cells in the follicle-sinus complexes of muzzle skins of rabid dogs Journal of virological methods · 2016 · 11 citations
    16. A pure, monolayer culture of Merkel cells from sinus hair follicles of the rat Neuroscience letters · 1996 · 11 citations
    17. LRIG1 is a positive prognostic marker in Merkel cell carcinoma and Merkel cell carcinoma expresses epithelial stem cell markers Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · 2021 · 10 citations
    18. Anatomical Mapping and Density of Merkel Cells in Skin and Mucosae of the Dog ˜The œanatomical record · 2016 · 6 citations
    19. Transduction‐induced overexpression of Merkel cell T antigens in human hair follicles induces formation of pathological cell clusters with Merkel cell carcinoma‐like phenotype Experimental dermatology · 2021 · 5 citations
    20. Merkel cell polyomavirus infection and persistence modelled in skin organoids 2025 · 2 citations
    21. Beta Human Papillomavirus and Merkel Cell Polyomavirus in Skin Neoplasms International Journal of Dermatology and Venereology · 2020 · 2 citations
    22. A pure, monolayer culture of Merkel cells from sinus hair follicles of the rat Neuroscience letters · 1996 · 2 citations
    23. Follicular induction and CK20+ Merkel cells overlying cutaneous focal mucinosis Journal of cutaneous pathology · 2018 · 1 citations
    24. Growth of Nerve Fibers to Merkel Cells Observed in Co-Culture of Sensory Ganglia and Sinus Hair Follicles 2003 · 1 citations
    25. 329 In vitro co-culture models of merkel cell-neurite complex in touch domes Journal of Investigative Dermatology · 2021
    26. LB1681 Risk of merkel cell carcinoma progression after treatment discontinuation in patients with an objective response to anti-PD-(L)1 immunotherapy 2023
    27. Near missed diagnosis of Merkel Cell Carcinoma in a young immunocompetent woman with a recurrent left-arm mass: A case report Authorea (Authorea) · 2023
    28. 578 Addressing the missing components for appropriate surveillance of Merkel cell carcinoma patients: Detailed recurrence data and an integrated risk analysis approach Journal of Investigative Dermatology · 2019
    29. Genetic and Environmental Factors that Control Merkel Cell Development and Survival D-Scholarship@Pitt (University of Pittsburgh) · 2017
    30. Role of BK channels and Kv4.2 channels in the electrophysiological properties of Merkel cells in rat whisker hair follicles Journal of Neurophysiology · 2025