Transduction-Induced Overexpression of Merkel Cell T Antigens in Human Hair Follicles Induces Formation of Pathological Cell Clusters with Merkel Cell Carcinoma-Like Phenotype

    August 2021 in “ Experimental dermatology ”
    Thibault Kervarrec, Jérémy Chéret, Ralf Paus … David Schrama
    Studysummary This study suggests that Merkel cell polyomavirus T antigen-positive cells resembling Merkel cell carcinoma may originate from epithelial cells in human hair follicles, potentially informing future transgenic mouse models for this cancer.
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