3 citations
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August 2025 in “Cell” Fibroblast bioelectric signaling can promote hair growth and may help treat hair loss.
3 citations
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January 2016 In this study, NuMA's microtubule-binding domain was found to be crucial for correct spindle orientation and skin differentiation, with its loss leading to neonatal lethality in mice.
March 2026 in “Frontiers in Cell and Developmental Biology” This review reports that transcriptional and epigenetic mechanisms in epithelial stem cells guide their fate in the epidermis and hair follicles, crucial for skin homeostasis, but disruptions can lead to disease.
January 2026 in “Pharmaceutics” This review highlighted recent advances in nanocarrier-based topical delivery systems for skincare, emphasizing their potential to enhance ingredient stability, penetration, and targeted release while addressing specific pathophysiological skin concerns.
October 2025 in “Physiologia” In this exploratory in vitro study, treatment with spermidine increased cell viability and altered gene expression in human epidermal keratinocytes, suggesting potential benefits to cellular health and function, though effects on mitochondrial markers were not significant.
August 2024 in “Receptors” This review highlights the crucial role of vitamin D signaling in epidermal stem cells during skin wound healing, emphasizing its distinct functions from calcium metabolism and its importance in genomic regulation mediated by the vitamin D receptor.
April 2021 in “Animal Bioscience” This study found that 5-aminolevulinic acid significantly improved chicken sperm motility and increased mitochondrial membrane depolarization, while decreasing ATP levels.
This study found that upper-bulge epidermal stem cells in mouse hair follicles are specialized for nerve interactions, crucial for forming tactile sensory units, and influence touch responses via EGFL6 and αv integrin pathways.
In this study, upper-bulge epidermal stem cells in mouse hair follicles were shown to play a role in forming tactile sensory units by creating an extracellular matrix that supports nerve interactions.
May 2018 in “International journal of cell science & molecular biology” This article discusses the biology of cosmetic aging and the chemical pathways involved, emphasizing research advancements that aid clinicians in rejuvenating skin and increasing scalp hair density, but it provides no new results.
January 2018 in “Indian Dermatology Online Journal” This case report describes a nine-year-old girl with juvenile dermatomyositis and alopecia areata, suggesting a possible etiological link between these coexisting immune-mediated diseases, a previously unreported association.
June 2025 in “Голова и шея.” This study observed changes in the electrical and viscoelastic properties of erythrocytes, as well as hemostatic system activation, in women with alopecia following COVID-19 infection, potentially contributing to alopecia development and informing treatment strategies.
October 2022 in “Frontiers in Bioengineering and Biotechnology” This study demonstrated that in a mouse model of androgenic alopecia, PLGA-DUT/siAR@DPCM nanoparticles effectively delivered drugs to hair follicles, suppressed androgen-related targets, promoted cell proliferation, and showed significant therapeutic effects with minimal adverse effects, suggesting their potential for clinical application.
13 citations
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August 1991 in “The Journal of the American Osteopathic Association” This research found evidence of inflammatory involvement in androgenetic alopecia, with higher deposition of certain immune components in the scalp of affected patients compared to those without baldness.
October 2023 in “Current Issues in Molecular Biology” In this study, researchers observed that the YH complex, made from Astragalus membranaceus and Cinnamomum cassia, promoted hair regrowth and increased hair shaft thickness in mice, potentially through increased growth factors and Wnt/β-catenin signaling, suggesting its use for treating various forms of hair loss.
January 2022 in “Indian Journal of Paediatric Dermatology” This case study reports that patchy nonscarring alopecia without systemic involvement can be an atypical initial indication of juvenile onset systemic lupus erythematosus.
March 2013 in “Hair transplant forum international” This article discusses the role of inflammation in causing various types of alopecia but reports no clinical results; the author notes an ongoing interest in the topic.
226 citations
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May 2004 in “Journal of Biological Chemistry” This study identified collagen XXII as a novel extracellular matrix protein specifically present at tissue junctions, where it functions as a cell adhesion ligand for skin epithelial cells and fibroblasts.
166 citations
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September 2011 in “The Journal of Cell Biology” This study found that the p63 transcription factor plays a role in epidermal morphogenesis by regulating Satb1 expression, impacting chromatin architecture and gene expression in epidermal progenitor cells.
102 citations
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April 2014 in “PloS one” In this study, Wharton’s Jelly Mesenchymal Stem Cells, cultured with human platelet lysate, showed enhanced wound-healing capabilities and multilineage differentiation potential, distinguishing them from bone marrow-derived stem cells and presenting exciting prospects for regenerative medicine.
79 citations
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March 2017 in “Dermatologic clinics” This review discusses the complex systemic nature of vitiligo and its associations with autoimmune conditions, emphasizing the need for increased understanding and awareness of related comorbidities and psychological effects.
73 citations
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November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” This review examines histochemical and immunohistochemical markers to differentiate apocrine and eccrine sweat glands, highlighting their distinct markers, though it reports no new clinical findings.
67 citations
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July 2016 in “Reviews in Endocrine and Metabolic Disorders” This review discusses the complex relationship between stress and various skin conditions, highlighting the role of the skin in the stress response and the brain-skin communication pathways, but reports no new research findings.
65 citations
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November 2013 in “The EMBO Journal” HDAC1 is crucial for skin development and preventing tumors.
52 citations
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August 1978 in “Journal of Applied Polymer Science” Human hair's ability to get wet is complex and can change with treatments, damage, and environment.
23 citations
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July 2020 in “Aging Cell” In this study, researchers found that glycan profiles in epidermal stem cells differed between young and old mice, suggesting these changes may serve as molecular markers for aging.
10 citations
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March 2016 in “Development Growth & Differentiation” This study developed a bioengineering method to reconstruct embryonic dorsal skin from dissociated chick skin cells, allowing feather buds to form and grow in vitro, influenced by epithelial-mesenchymal interactions.
3 citations
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April 2025 in “Advanced Healthcare Materials” In this study, researchers developed hyaluronic acid derivatives functionalized with nitric oxide photodonors for light-activated skin treatments, finding that the compounds released NO under blue light and enhanced keratinocyte proliferation and migration, suggesting potential for therapeutic use.
2 citations
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February 2025 in “International Journal of Molecular Sciences” This study identified key proteins, such as Sfrp1 and Ppard, involved in the complex and dynamic regulation of yak hair follicle growth and degeneration across different stages, offering insights into yaks' adaptation to highland environments.
2 citations
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December 1973 in “Calcified tissue research” This study proposed a hypothesis for cutaneous calcinosis, suggesting that feeding DHT and subsequent epilation lead to ATP release and calcium orthophosphate formation, initiating calcification in rats.