Coexistence of Dermatomyositis and Alopecia Areata: Insight into Pathogenesis

January 2018 in “ Indian Dermatology Online Journal ”

Aastha Gupta, Pooja Arora, R. K. Gautam

alopecia areata dermatomyositis methotrexate prednisolone interferon-α major histocompatibility complex class I molecules AA DM MHC class I

TLDR DM and AA may share a common cause.

A 9-year-old girl with juvenile dermatomyositis (DM) and alopecia areata (AA) showed significant improvement in both conditions after treatment with methotrexate and prednisolone. The coexistence of DM and AA, previously unreported, suggested a potential common etiological link, possibly involving interferon-α (IFN-α) and immune responses. The study highlighted the need for further research into the pathogenesis of these immune-mediated diseases.

View this study on journals.lww.com →

Discuss this study in the Community →

Research cited in this study

1 / 1 results

research Alopecia Areata During Interferon Alpha-2b and Ribavirin Therapy

35 citations, January 2002 in “Dermatology”

A woman's hair loss during treatment with specific hepatitis C drugs grew back after stopping the medication.

Related Community Posts Join

6 / 1000+ results

community Alopecia Areata Question

in Treatment 2 upvotes 3 years ago

A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

community mbp alopecia areata or vitamin deficiency

in Chat 4 months ago

A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

community Olumiant alternative for Alopecia Areata?

in Treatment 1 upvotes 1 year ago

A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

community Covid (likely) induced alopecia areata - now 2nd round of Covid, what can I expect?

in Treatment 1 upvotes 1 year ago

After experiencing hair loss due to alopecia areata following COVID-19 vaccination and infection, the individual saw improvement with steroid treatments and Olumiant. They paused Olumiant during a second COVID-19 infection and expressed concern about potential hair loss flare-ups.

community Onion Juice - An effective topical treatment for Alopecia Areata 🧬

in Treatment 1 year ago

Onion juice, when applied topically, is an effective treatment for Alopecia Areata, showing significant hair regrowth in both males and females. The study suggests it could be interesting to test its effectiveness on Androgenic Alopecia.

community Nearly 40% of Adults with Alopecia Areata Taking OLUMIANT® 4-mg Saw at Least 80% Scalp Hair Coverage at 52 Weeks

in Research/Science 6 upvotes 2 years ago

Nearly 40% of adults with alopecia areata achieved at least 80% scalp hair coverage after 52 weeks of taking OLUMIANT® 4-mg. The conversation distinguishes this success from androgenetic alopecia, which is a different type of hair loss.

Related Research

1 / 1 results

research Serum Zinc Concentration in Patients With Alopecia Areata

October 2023 in “Acta dermato-venereologica (Print)”

People with severe hair loss have lower zinc levels in their blood.