research Alopecia Areata: A Review of Diagnosis, Pathogenesis, and the Therapeutic Landscape
New treatments for alopecia areata show promise, but standardized guidelines are needed.
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research MCPIP1 Controls Effects of Myeloid Cells on Skin Carcinogenesis and Hair Growth
MCPIP1 in myeloid cells is important for skin cancer development and healthy hair growth.
research A Guide to Studying Human Hair Follicle Cycling In Vivo
The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
research Stimulating Effect of Adrenalectomy on Hair Growth and Melanin Deposition in Black Rats Fed Diets Adequate and Deficient in the Filtrate Factors of Vitamin B1
Adrenalectomy boosts hair growth and melanin in black rats, even with vitamin B¹ deficiency.
research Hair Microscopy: An Easy Adjunct to Diagnosis of Systemic Diseases in Children
Hair microscopy is a simple and cost-effective method to help diagnose systemic diseases in children.
research Evaluation of the Efficacy of Intense Pulsed Light in Skin Rejuvenation
Intense Pulsed Light treatments significantly improve signs of aging and sun damage on the skin.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research Carvone Decreases Melanin Content by Inhibiting Melanoma Cell Proliferation via the Cyclic Adenosine Monophosphate (cAMP) Pathway
Carvone helps treat skin issues by reducing melanin and stopping harmful cell growth.
research Epimedium Brevicornum Maxim Extract Enhances Melanin Biosynthesis and Melanosome Biogenesis/Transfer
Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.
research Oral Zinc Sulphate Causes Murine Hair Hypopigmentation And Is A Potent Inhibitor Of Eumelanogenesis In Vivo
Oral zinc sulphate reduces dark hair color in mice.
research The Antimycotic Agent Clotrimazole Inhibits Melanogenesis by Accelerating ERK and PI3K/Akt-Mediated Tyrosinase Degradation
Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.
research 3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes
A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
research Efficacy of an Agonist of α-MSH, the Palmitoyl Tetrapeptide-20, in Hair Pigmentation
Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.
research Pigmentation Effect of Rice Bran Extract in Hair Follicle-Like Tissue and Organ Culture Models
Rice bran extract boosts melanin production in hair follicles.
research A Comparative Study of Skin Transcriptomes and Histological Observations for Black and White Hair Colors of Giant Panda
The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.
research Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin
Dermal factors are crucial in regulating melanin production in skin.
research Promotion of Hair Regrowth in Androgenetic Alopecia with Supplemented Erzhi Wan: Exploring Its Mechanism Using Network Pharmacology and Molecular Docking
Supplemented Erzhi Wan may help regrow hair in male pattern baldness by affecting certain cell signaling pathways.
research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity
The human scalp hair bulb contains different types of melanocytes with varying abilities to produce melanin.
research Utility of Horizontal Sections of Scalp Biopsies in Differentiating Between Androgenetic Alopecia and Alopecia Areata
Horizontal sections of scalp biopsies are useful for telling the difference between Androgenetic Alopecia and Alopecia Areata.
research Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars
Condensed nanofat with fat grafts effectively improves atrophic facial scars.
research Distribution of Glycolipid and Unsaturated Fatty Acids in Human Hair
Human hair has more unsaturated fats inside than on the surface, and certain lipids may help bind the outer and inner layers together.
research Evaluation of Wavelength-Dependent Hair Growth Effects on Low-Level Laser Therapy: An Experimental Animal Study
The 830-nm wavelength was most effective at promoting hair growth in rats using low-level laser therapy.
research Biological Effects of Electrical Epilation on Human Hair Follicles and Perifollicular Skin Ex Vivo
Electrical epilation damages hair follicles and surrounding skin, likely preventing hair regrowth.
research Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation
Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
research The Silver Locus Product (Silv/gp100/Pmel17) as a New Tool for the Analysis of Melanosome Transfer in Human Melanocyte–Keratinocyte Co-Culture
The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
research Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation
Applying a specific inhibitor lightens skin and hair color.
research Pharmacological BACE1 and BACE2 Inhibition Induces Hair Depigmentation by Inhibiting PMEL17 Processing in Mice
Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
research Keratinocytes Regulate the Function of Melanocytes
Keratinocytes control how melanocytes work.
research Therapeutic Potential of Patient iPSC-Derived Melanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
research Re-Evaluating Cyclosporine A as a Hair Growth–Promoting Agent in Human Scalp Hair Follicles
Cyclosporine A promotes hair growth and prolongs the active growth phase in human hair follicles, but may work differently than in rodents.