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The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.

In September 2016, there were major advancements and promising clinical trials in stem cell research and regenerative medicine.

The developed system could effectively treat hair loss and promote hair growth.

JAM-A helps hair regrowth in alopecia areata by protecting VCAN in skin cells.

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Targeting and modifying the stem cell niche can improve regenerative therapies.

Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.

Human dermal stem cells can become functional skin pigment cells.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

Creating fully functional artificial skin for chronic wounds is still very challenging.

The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

Nanotechnology shows promise for better chronic wound healing but needs more research.

Metabolic signals and cell shape influence how cells develop and change.

Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.

Human stem cells can help form hair follicles in mice.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

A surface with VEGF can specifically capture endothelial cells from flowing fluids.

SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.

Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.

Special cell particles from macrophages can help hair grow.

Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.

Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.

Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.

Special particles from skin cells can promote hair growth by activating a specific growth signal.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.

Stem cells can help other stem cells by producing supportive factors.

Human sweat glands have a type of stem cell that can grow well and turn into different cell types.