Search

everythinglearnresearchcommunity

for

Search:↓

The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.

SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Notch signaling disruptions can cause various skin diseases.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Nanotechnology is improving drug delivery and targeting, with promising applications in cancer treatment, gene therapy, and cosmetics, but challenges remain in ensuring precise delivery and safety.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.

Seresto® collar is safe to use with Advocate® and Profender® on dogs and cats.

Different types of skin stem cells can change and adapt, which is important for developing new treatments.

Plant-derived extracellular vesicles show promise for treating diseases like cancer and inflammation.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

Hair microRNAs could be effective biomarkers for diagnosing scleroderma.

Proper mineral supplementation in cow-calf operations prevents health issues and economic losses.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

The research identified genes that explain why some sheep have curly wool and others have straight wool.