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Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Nerves are crucial for the regeneration of various body parts in many animals.

The gene Msx2 is crucial for hair follicle regeneration during wound healing.

Mice can regrow hair on wounds due to specific cell interactions and mechanical forces not seen in rats.

Zebrafish need MYC and FGF to regenerate inner ear hair cells.

Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

Lanyu pigs show that partial-thickness wounds can partially regenerate important skin structures, which may help improve human skin healing.

Careful selection of mice by genetics and age, and controlled housing conditions improve the reliability of hair regrowth in wound healing tests.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.

Mice can regenerate ear tissue without the p53 protein.

Hair follicle stem cells help skin heal and grow during stretching.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.

Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.

Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.

Wounds can cause new hair growth in adult mice, influenced by Wnt signaling.

African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.

Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.