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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Treating hair loss in both men and women is effective and improves quality of life.

Identified genes linked to male-pattern baldness may help develop new treatments.

Alopecia in animals can be hereditary, congenital, or acquired, with treatments and outcomes varying widely.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Gene variation affects prostate issues and hair loss.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.

Sex hormones likely don't affect atopic dermatitis in adolescents and adults.

Vitamin A deficiency changes cattle hair structure, while pregnancy may improve it, suggesting hair can indicate cattle health.

Homeopathic remedies can help manage PCOS symptoms in girls aged 17-21.

Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.

Korean patients with PCOS often have skin problems like acne and excess hair, with different symptoms based on their specific PCOS type.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Men with low testosterone should be carefully evaluated and monitored before and during treatment.

Finasteride's link to health issues like male breast cancer, infertility, and prostate cancer needs more research through placebo-controlled trials to confirm.

More research is needed on the health effects of hormone therapy for transgender and nonbinary people.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Retinoic acid affects male and female muscle energy use and function differently.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

New and existing treatments for hair loss show promise, with some being more effective for men and others for women.

Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.