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Lower CD200R1 on certain immune cells is linked to more severe rheumatoid arthritis and immune imbalance.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.

Macrophage activation syndrome can be a deadly first sign of systemic lupus erythematosus.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

Using stem cells from fat tissue can significantly improve wound healing in dogs.

Honokiol helps protect skin from damage and aging caused by cigarette smoke.

The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.

Hairless HRS/J mice resist Bacillus anthracis skin infections due to high numbers of immune cells, not because they lack hair follicles.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Modified stem cells from umbilical cord blood can make hair grow faster.

People with alopecia areata have higher insulin resistance.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

New treatments for hair loss show promise but need more research to confirm safety and effectiveness.

PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

EMS and EF both show similar skin and fascia changes, but EMS has more severe symptoms and nerve inflammation.

Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.

Zinc is effective for treating various skin conditions, including warts and acne.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Some drugs, especially biologics, can cause skin reactions that look like other skin diseases, and stopping the drug usually helps clear up these reactions.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

New treatments and diagnostic methods for various animal skin conditions showed promising results.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.