TLDR People with alopecia areata have higher insulin resistance.
The study conducted from February 2009 to December 2010 included 51 patients with alopecia areata (AA) and 36 controls, finding that AA patients had significantly higher levels of insulin, c-peptide, and Homeostasis Model Assessment-Insulin Resistance (HOMA-IR), as well as higher blood pressure and a greater prevalence of hyperinsulinemia and metabolic syndrome. The study concluded that insulin resistance is increased in AA patients, which may be related to higher levels of inflammatory cytokines and activation of the hypothalamic-pituitary-adrenal axis, although these were not directly measured. Further research with larger sample sizes was recommended to explore the potential immunopathogenetic link between AA and IR.
42 citations,
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March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Patients with severe alopecia areata have higher levels of MIF, which decrease after successful treatment.
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February 2023 in “Journal of Personalized Medicine” Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.
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