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The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Cathepsin L is essential for normal hair growth and development.

The study suggests that a new protease inhibitor can make hair harder to pull out, potentially reducing hair loss.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Zebrafish larvae are used to study and find treatments for ear cell damage because they are easier to observe and test than mammals.

FLCN helps control iron levels in cells.

Differences in growth factors in platelet-rich plasma therapy for hair loss can vary between patients and can be influenced by the devices used, possibly leading to inconsistent results.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Fat cells in the skin help start healing and form important repair cells after injury.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.