19 citations
,
October 2020 in “Journal der Deutschen Dermatologischen Gesellschaft” This review found that despite varied levels of stigmatization reported in studies, hair loss generally leads to stigmatization and a reduced quality of life, but specific research on this stigma is limited.
19 citations
,
July 2020 in “EBioMedicine” In this study, the researchers identified a variant in the CCHCR1 gene associated with an alopecia areata subtype characterized by impaired keratinization and autoimmune events.
19 citations
,
September 2016 in “Pharmacotherapy” This study found that the risk of persistent sexual dysfunction was higher in men who stopped using finasteride 1 mg compared to omeprazole users.
19 citations
,
July 2012 in “Biotechnic & Histochemistry” This study observed that decreased nucleolar organizing region protein synthesis in hair root cells is correlated with hair loss in humans.
19 citations
,
January 2012 in “Biomolecules & Therapeutics” This study found that Grateloupia elliptica extract may help treat hair loss by promoting dermal papilla cell proliferation, inhibiting 5α-reductase, and reducing inflammation in various cell types.
19 citations
,
January 2012 in “Dermato-endocrinology” This study suggests that moderate elevated prolactin levels are unlikely to cause significant hair loss in women, but still warrant further diagnostic investigation to rule out a prolactin-producing pituitary tumor.
19 citations
,
September 2009 in “PubMed” This case report highlights a patient who developed acute hepatitis after consuming an oral green tea derivative for hair loss, with recovery following the cessation of the product.
19 citations
,
June 2009 in “Seminars in cutaneous medicine and surgery” This article discusses diagnostic challenges and management approaches for hair loss in women of color, emphasizing the importance of clinical examinations and education to prevent and manage traction alopecia.
19 citations
,
February 2008 in “Archives of Dermatological Research” This study observed that mast cells and increased collagen and elastic fibers in the scalp may contribute to male pattern hair loss, but additional research is needed for further understanding.
19 citations
,
January 2001 in “Internal Medicine” This case report demonstrates a strong association between protein-losing enteropathy and systemic lupus erythematosus, with symptoms and conditions improving with prednisolone treatment.
18 citations
,
September 2018 in “Current Pharmaceutical Design” This review discusses the recent progress of medicinal plants for treating hair loss and their suggested mechanisms, but reports no new clinical results.
18 citations
,
February 2017 in “Journal of Cosmetic Dermatology” This study reports that mesotherapy for androgenetic alopecia may paradoxically lead to hair loss and scarring, highlighting the need for improved regulation and monitoring of this treatment.
18 citations
,
July 2015 in “Journal of cosmetic dermatology” This study observed that combining hair dyeing with sodium hydroxide relaxers drastically increased protein loss in Caucasian virgin dark brown hair, while ammonium thioglycolate or guanidine hydroxide relaxers caused less damage.
18 citations
,
April 2013 in “Inflammatory Bowel Diseases” This review discusses the various potential causes of hair loss in patients with inflammatory bowel disease, including telogen effluvium from disease flares, but provides no prevalence data; the authors outline a practical assessment and management approach.
18 citations
,
August 2012 in “Clinical and Experimental Dermatology” This study concluded that a 3% IGF-1 liposomal gel improved hair thickness and growth in hamsters without inducing significant hepatotoxicity or myelotoxicity, suggesting its potential as a safe hair-loss treatment.
18 citations
,
March 2000 in “PubMed” This study found that male pattern hair loss significantly negatively impacts men aged 18 to 40 in France, Italy, Germany, and the UK, with perceived noticeability contributing to these effects.
18 citations
,
October 1984 in “International Journal of Dermatology” This article reviews the relationship between hair loss and lithium but does not provide any new clinical findings.
17 citations
,
April 2021 in “Frontiers in Pharmacology” This review discusses the role of Nrf2 in hearing loss and its potential as a target for developing hearing protection drugs, but reports no new clinical results.
17 citations
,
July 2019 in “Scientific reports” This study investigated lipid loss in hair caused by surfactants and found that surface and internal modifications can significantly protect different lipids from depletion, with internal modification preventing 52.0 to 81.3% of lipids in certain groups.
17 citations
,
October 2015 in “Medicine and Pharmacy Reports” This article reviews current research on animal models for hair regrowth treatments and reports no new findings; it highlights the need for studies comparing therapy efficiency and long-term safety.
17 citations
,
February 2011 in “International Journal of Cosmetic Science” This study found that individual differences between pigmented and unpigmented hair fibers in Old Order Mennonites suggest grey hair may be perceived as drier and less manageable due to small mechanical and moisture changes.
17 citations
,
August 2002 in “AIDS” This study observed that patients undergoing indinavir/ritonavir therapy for HIV-1 frequently experienced reversible alopecia, likely due to retinoid-like effects, but these were independent of other retinoid-like skin manifestations.
17 citations
,
November 1982 in “Annals of Internal Medicine” This report details two cases of accelerated hair loss potentially related to 5-aminosalicylic acid enema therapy in patients with ulcerative proctitis.
16 citations
,
April 2020 in “JAMA dermatology” More inflammation leads to faster and worse hair loss in women with frontal fibrosing alopecia.
16 citations
,
February 2017 in “Dermatology and Therapy” This study established and validated a visual scale to assess hair shedding in women with thick hair, finding it effective in distinguishing greater hair loss among women with female pattern hair loss compared to those without.
16 citations
,
June 2015 in “Seminars in Cutaneous Medicine and Surgery” This article discusses the challenges of diagnosing and managing hair disorders in patients with skin of color, especially conditions more prevalent in those of African descent, and provides no new clinical results.
16 citations
,
January 2015 in “Annals of Dermatology” In this study, trichoscopic features aiding differential diagnosis of alopecia in Korean patients were found to be similar to those in Caucasians, but pigment pattern frequencies differed due to racial characteristics.
16 citations
,
May 2013 in “Australasian Journal of Dermatology” In this study, detailed examinations of alopecic lesions in two female Cronkhite-Canada syndrome patients suggested hair regrowth might occur without systemic corticosteroids if not required for gastrointestinal treatment, and hair loss may begin with anagen-telogen transition.
16 citations
,
January 2012 in “International Journal of Rheumatology” In this study, weight gain and hair loss were reported as adverse effects of anti-TNF therapy in patients with rheumatic diseases, leading some to discontinue treatment.
15 citations
,
February 2019 in “Journal of clinical medicine” In this animal study, atorvastatin co-administered with trastuzumab reversed trastuzumab-induced cognitive impairment (chemo-brain) and improved its anti-cancer efficacy without causing hair loss.