research Sulfatase Inhibitors: A Patent Review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
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research Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex
Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.
research Different Gene Expression Profile Observed in Dermal Papilla Cells Related to Androgenic Alopecia by DNA Macroarray Analysis
Hair loss in balding individuals is linked to changes in specific hair growth-related genes.
research Repairing the Lungs One Breath at a Time: How Dedicated or Facultative Are You?
Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
research Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia
New genes found linked to balding, may help develop future treatments.
research Hunting the Genes in Male-Pattern Alopecia: How Important Are They, How Close Are We and What Will They Tell Us?
Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.
research The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells
Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal, and Prostate Cancer
Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
research Spontaneous Hair Follicle Germ Formation In Vitro, Enabling The Large-Scale Production Of HFGs For Regenerative Medicine
Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.
research Gelatin-Chondroitin-6-Sulfate-Hyaluronic Acid Scaffold Seeded with Vascular Endothelial Growth Factor 165 Modified Hair Follicle Stem Cells as a Three-Dimensional Skin Substitute
Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.
research An Analysis of Follicular Punches, Mechanics, and Dynamics in Follicular Unit Extraction
Using sharp tools and the right techniques in hair transplant surgery leads to less damage to hair follicles.
research Rosemary Extracts Containing Carnosic Acid and Carnosol Are Potent Quorum Sensing Inhibitors of Staphylococcus Aureus Virulence
Rosemary extracts with carnosic acid and carnosol can reduce the harmfulness of Staphylococcus aureus without stopping its growth.
research Lymphatic Vessels Interact Dynamically with the Hair Follicle Stem Cell Niche During Skin Regeneration In Vivo
Lymphatic vessels are essential for hair follicle growth and skin regeneration.
research Establishment of an In Vitro Organoid Model of Dermal Papilla of Human Hair Follicle
Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
research Anti-Androgenic Effect of Sesquiterpenes Isolated from the Rhizomes of Curcuma Aeruginosa Roxb.
Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.
research Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration
Hoxc genes control hair growth through Wnt signaling.
research An Observational Retrospective Evaluation of 79 Young Men with Long-Term Adverse Effects After Use of Finasteride Against Androgenetic Alopecia
Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.
research The CLE40 and CRN/CLV2 Signaling Pathways Antagonistically Control Root Meristem Growth in Arabidopsis
CLE40 and CRN/CLV2 pathways have opposite effects on root growth in Arabidopsis.
research TGF-β2 Is Specifically Expressed in Human Dermal Papilla Cells and Modulates Hair Folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
research Expression Patterns of MITF During Human Cutaneous Embryogenesis: Evidence for Bulge Epithelial Expression and Persistence of Dermal Melanoblasts
Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
research Investigation of Human Hair Fibers Using Lateral Force Microscopy
Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.
research Analysis of Protein Interactions by Surface Plasmon Resonance
Surface Plasmon Resonance is a useful tool for studying protein interactions and has potential for future technological advancements.
research Nanotechnology-Based Cosmetics for Hair Care
Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.
research Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis
Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
research Eph/Ephrin Signaling in Epidermal Differentiation and Disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research Proliferation, But Not Apoptosis, Is Associated With Distinct Beta-Catenin Expression Patterns in Non-Small-Cell Lung Carcinomas
Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.
research Analysis of 1,25-Dihydroxyvitamin D3 Receptors in Basal Cell Carcinomas
Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.
research Control by a Hair’s Breadth: The Role of MicroRNAs in the Skin
MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
research Congenital Hair Loss Disorders: Rare, But Not Too Rare
Some hair loss disorders are caused by genetic mutations affecting hair growth.
research Conversion of the Nipple to Hair-Bearing Epithelia by Lowering Bone Morphogenetic Protein Pathway Activity at the Dermal-Epidermal Interface
Blocking a specific protein signal can make hair grow on mouse nipples.