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Melatonin implants and long daylight hours alter the timing of hormone release and hair growth in mouflon sheep.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Long-term use of oral contraceptives, especially starting before age 20, may increase the risk of early-onset breast cancer.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

New treatments for long-lasting erections improve outcomes but must be timely to avoid lasting damage.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Acne is a chronic skin condition not caused by poor hygiene or diet, and it requires long-term treatment and patient education.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

The Polish Society of Dermatology recommends treatments for alopecia areata that vary by severity, including topical and systemic medications, with long-term maintenance important for management.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.

The document concludes that each reviewed medical book is useful for its specific area in pediatric care, especially the "Neonatal Formulary" for neonatal drug information.

Peripheral nerve blocks are a safe and effective way to treat various headaches and provide lasting pain relief.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Systemic corticosteroids can help treat rapidly spreading vitiligo but require more research for safer use.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.

Low-dose anti-androgen drugs and certain drug combinations are effective for hirsutism, and insulin sensitizers show promise, especially for those with polycystic ovarian syndrome.

The document suggests a young mother use effective contraception like the Copper-T IUD while considering her health and the need for STD prevention.