research Repositioning Study of Flubendazole for Treating Lung Cancer and Meningoencephalitis Using an Oral Lipid Nanosystem
Flubendazole in a nanoemulsion can potentially treat lung cancer and cryptococcal meningitis effectively and safely.
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research Protective Role of Melatonin and Its Metabolites in Skin Aging
Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
research Peripheral Neuroprotective and Immunomodulatory Effects of 5α-Reductase Inhibitors in Parkinson's Disease Models
Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.
research Ethosomes: An Exciting and Promising Alcoholic Carrier System for Treating Androgenic Alopecia
Ethosomes are a promising method for treating hair loss by delivering drugs directly to the scalp.
research Omega 3 Fatty Acid-Enriched Nanoemulsion of Thiocolchicoside for Transdermal Delivery: Formulation, Characterization, and Absorption Studies
The new formulation improved the skin absorption of the drug Thiocolchicoside.
research Hair as a Retrospective Calendar of Cortisol Production—Increased Cortisol Incorporation into Hair in the Third Trimester of Pregnancy
Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.
research Tea Tree Oil Concentration in Follicular Casts After Topical Delivery: Determination by High-Performance Thin Layer Chromatography Using a Perfused Bovine Udder Model
Different tea tree oil mixtures absorb into hair follicles at varying levels, with microemulsion being the most effective.
research Purification and Characterization of Rat Liver Minoxidil Sulphotransferase
Enzyme purified and characterized for minoxidil sulphation in rat liver.
research Iontophoretic Transdermal Delivery of Finasteride in Vesicular Invasomal Carriers
Finasteride delivery through skin improved using invasomes and iontophoresis.
research Development and Evaluation of Polyherbal Antidandruff Hair Oil
The polyherbal hair oil effectively reduces dandruff and promotes hair growth.
research Cutaneous Distribution of Orally Administered Itraconazole in Guinea Pigs Studied by Autoradiography
Oral itraconazole effectively reaches and treats deep skin layers in guinea pigs.
research Advances of Non-Ionic Surfactant Vesicles (Niosomes) and Their Application in Drug Delivery
Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.
research Niosomes as a Vesicular Carrier for Topical Administration of Minoxidil: Formulation and In Vitro Assessment
Niosomes improve minoxidil skin penetration for hair loss treatment.
research Sulfatase Inhibitors: A Patent Review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research Binary and Ternary Inclusion Complexes of Finasteride in HPβCD and Polymers: Preparation and Characterization
Finasteride complexes with HPβCD and polymers improve solubility, potentially enhancing hair loss treatment.
research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Investigation of Drug Partition Property in Artificial Sebum
The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
research The Use of Photodynamic Therapy for Treatment of Acne Vulgaris
Photodynamic Therapy is an effective treatment for mild to severe acne.
research Percutaneous Absorption of a New Antiandrogen Included in Liposomes or in Solution
Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.
research Developing Formulations for Drug Follicular Targeting: Nanoemulsions Loaded with Minoxidil and Clove Oil
Nanoemulsions with minoxidil and clove oil effectively target hair follicles for better alopecia treatment.
research Synthesis and In Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-Oxo-4-Androstene-17β-Carboxamides as 5α-Reductase Inhibitors and Antiandrogens
The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
research Effect of Tocopheryl Polyethylene Glycol Succinate on the Percutaneous Penetration of Minoxidil from Water/Ethanol/Polyethylene Glycol 400 Solutions
Adding TPGS to minoxidil solutions can improve skin penetration and retention, especially in water and PEG 400-based solutions.
research Nutraceuticals for Healthy Skin Aging
Certain nutrients can help keep skin healthy as we age.
research Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers
Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
research In Vitro Skin Permeation of Hinokitiol Loaded in Vesicles Composed of Behenyltrimethylammonium Chloride and Stearic Acid
Vesicles made of behenyltrimethylammonium chloride and stearic acid can triple the skin absorption of hinokitiol, which may help with hair growth.
research Optimization of Minoxidil Microemulsions Using Fractional Factorial Design Approach
The study found a way to improve a skin-applied minoxidil formula using a specific design method.
research ERK1/2 Pathway Involvement in Enhancement of Fatty Acids from Phaeodactylum Tricornutum Extract on Hair Follicle Cell Proliferation
Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.
research Melatonin
Melatonin may help with sleep issues, depression, and cancer, but more research is needed.
research Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing
The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.
research Transfollicular Drug Delivery: Is It a Reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.