Purification and Characterization of Rat Liver Minoxidil Sulphotransferase
September 1990
in “
Biochemical Journal
”
TLDR Enzyme purified and characterized for minoxidil sulphation in rat liver.
The paper describes the purification and characterization of rat liver minoxidil sulphotransferase (Mx-ST), an enzyme responsible for the sulphation of minoxidil in rat liver cytosol. The enzyme was purified using various chromatography procedures and was found to exist as a homodimer with a subunit molecular mass of approximately 35,000 Da. Mx-ST is related to a family of STs that are capable of sulphating small phenols such as PNP. The study provides information on the purification and characterization of Mx-ST in rat liver tissue.
