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Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Your skin is like an ecosystem, with its own community of microbes and substances that interact and affect its health.

Low vitamin D levels may affect ovulation and progesterone in infertile women.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Exosomes could be effective for improving skin health and treating skin diseases.

Proper nutrition can help manage PCOS symptoms and improve overall health.

New treatments for male hypogonadism are effective and should be personalized.

Father's finasteride use may affect son's fertility and testicular function.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

FGF21 can help reduce skin inflammation caused by C. acnes.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Individualized treatment plans, including lifestyle changes and specific medications, are crucial for managing PCOS in adolescents.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Anti-androgens can help reduce the effects of male hormones on the skin.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Fermented papaya and mangosteen in hair care products helped prevent hair loss and improve hair thickness.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.