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Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Dutasteride and finasteride affect different cell types differently.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.

Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Estrogen therapy can reduce skin aging but has cancer risks.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.