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Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Mutations in certain receptors can cause diseases and offer new treatment options.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

RORA may help regulate hair growth by affecting hair follicle stem cells.

Delta-opioid receptors affect skin cell circadian rhythms, possibly impacting wound healing and cancer.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Human skin has less GDNF and its receptor with age.

Sansevieria trifasciata Prain shows promise for treating hair loss by inhibiting androgen receptors.

Cattle skin has leptin which might control skin and hair growth.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Metabolic signals and cell shape influence how cells develop and change.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

Hairless protein can block vitamin D activation in skin cells.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Minoxidil can reduce functions related to androgen receptors.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

New injectable hydrogels with gelatin, metal, and tea polyphenols help heal diabetic wounds faster by controlling infection, improving blood vessel growth, and managing oxidative stress.