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Early hair loss in men could be a sign of non-cancerous prostate enlargement, and treating hair loss early might help prevent prostate issues later.

Women with myotonic dystrophy might get diseases related to male hormones because their body tissues are extra sensitive to these hormones.

Ca_v1.2 affects hair growth and could be a target for hair loss treatments.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Smaller nanoemulsions can penetrate skin and hair follicles better, which may be useful for delivering drugs and vaccines through the skin.

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

ACTH-dependent Cushing's syndrome linked to metastatic cervical cancer is rare and has high risks.

Metastatic cervical cancer can cause rare, severe Cushing's syndrome with high risk of death.

Smad2/3-dependent TGF-β signaling increases during wound healing.

The most common skin issues in females with Polycystic Ovary Syndrome (PCOS) are excessive hair growth, hair loss, oily skin, acne, dark skin patches, and skin tags, which may be linked to hormone and insulin levels.

Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Finasteride safely lowers DHT levels without affecting testosterone.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Many women in southern China have polycystic ovary syndrome, with some symptoms differing from Western women.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

Men with male pattern hair loss have different levels of certain hormones compared to men without hair loss.

Anti-Müllerian hormone is a specific marker for ovarian issues in women with conditions like PCOS.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.