Evaluation of Androgen-Dependent Skin Findings of Polycystic Ovary Syndrome (PCOS)

December 2022 in “ Gynecological Endocrinology ”

Gokhan Artar, Betul Tas, Gökçe Turan, Hasan Uckan

Studysummary This study found that among women with PCOS, higher HOMA-IR levels were associated with acanthosis nigricans, and increased DHEA-SO4, FAI, and FI values were linked to hirsutism.

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This study found that statin treatment significantly reduced androgen levels and improved symptoms of hyperandrogenism, such as hirsutism and acne, in women with polycystic ovary syndrome.

research Cutaneous Manifestations of Polycystic Ovary Syndrome

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This study found that acne, hirsutism, and other skin conditions are prevalent among Jordanian women with polycystic ovary syndrome, often linked to specific hormonal imbalances and higher BMI.

research Prevalence of Dermatologic Manifestations and Metabolic Biomarkers in Women with Polycystic Ovary Syndrome in North China

17 citations , September 2017 in “Journal of Cosmetic Dermatology”

In this study of women with PCOS, hirsutism strongly correlated with metabolic abnormalities, while acne and androgenic alopecia were not clear markers of biochemical hyperandrogenemia or metabolic dysfunction.

research Endocrine Evaluation of Hirsutism

29 citations , February 2017 in “International Journal of Women's Dermatology”

This article provides an endocrine perspective on evaluating and managing hirsutism but reports no new research findings.

research Evidence-Based Approach to Cutaneous Hyperandrogenism in Women

42 citations , July 2015 in “Journal of The American Academy of Dermatology”

This review discusses diagnostic and treatment considerations for women with cutaneous hyperandrogenism, noting therapeutic options are more effective for hirsutism and acne than for androgenetic alopecia, but reports no new clinical results.

research Cutaneous Manifestations of the Subtypes of Polycystic Ovary Syndrome in Korean Patients

16 citations , March 2014 in “Journal of the European Academy of Dermatology and Venereology”

This study found that acne was the most common dermatological manifestation in Korean women with polycystic ovary syndrome, particularly those with a specific combination of symptoms, showing distinct variations in serum hormonal and metabolic parameters.

Specific Dermatologic Features of Polycystic Ovary Syndrome and Its Association with Biochemical Markers of Metabolic Syndrome and Hyperandrogenism

research Specific Dermatologic Features of Polycystic Ovary Syndrome and Its Association with Biochemical Markers of Metabolic Syndrome and Hyperandrogenism

67 citations , February 2010 in “Acta Obstetricia et Gynecologica Scandinavica”

In this study, hirsutism in women with PCOS was strongly associated with hyperandrogenism and metabolic abnormalities, while acne and androgenic alopecia were not effective markers for hyperandrogenism.

research Visually Scoring Hirsutism

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This review examines various methods for assessing hair growth in women, highlighting the usefulness of the mFG visual scoring method for diagnosing hirsutism despite its limitations.

research Dermatologic Manifestations of Polycystic Ovary Syndrome

76 citations , January 2007 in “American Journal of Clinical Dermatology”

This review discusses the dermatologic features of PCOS as potential early indicators of the syndrome and notes that treatment of these conditions may enhance quality of life and psychological well-being, but it reports no new clinical results.

Current Recommendations for the Diagnostic Evaluation and Follow-Up of Patients Presenting with Symptomatic Polycystic Ovary Syndrome

research Current Recommendations for the Diagnostic Evaluation and Follow-Up of Patients Presenting with Symptomatic Polycystic Ovary Syndrome

19 citations , October 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology”

This review discusses the complexities in diagnosing polycystic ovary syndrome and emphasizes the need for individualized assessment based on each patient's specific symptoms and history, but reports no new results.

research Androgen Excess in Women: Experience with Over 1000 Consecutive Patients

947 citations , February 2004 in “The Journal of Clinical Endocrinology and Metabolism”

In this study, polycystic ovary syndrome was the most prevalent cause of androgen excess, and suppressive hormonal therapy improved hirsutism, menstrual dysfunction, and acne in most patients, though side effects were common.

research Prevalence of Polycystic Ovaries in Women with Androgenic Alopecia

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This study found that women with androgenic alopecia had a higher prevalence of polycystic ovarian morphology and higher androgen levels compared to controls, suggesting a strong association with PCO.

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This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.