The Effects of Statins on Hyperandrogenism in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    December 2021 in “ Reproductive Biology and Endocrinology ”
    Jianguo Chen, Chaoran Huang, Tongtong Zhang … Yuanbiao Guo
    Studysummary This study found that statin treatment significantly reduced androgen levels and improved symptoms of hyperandrogenism, such as hirsutism and acne, in women with polycystic ovary syndrome.
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    Research cited in this study 10

    1. Pharmacological Approaches to Controlling Cardiometabolic Risk in Women with PCOS International Journal of Molecular Sciences · 2020
    2. Cholesterol Homeostasis: Links to Hair Follicle Biology and Hair Disorders Experimental Dermatology · 2019
    3. Treatment Options for Hirsutism: A Systematic Review and Network Meta-Analysis The Journal of Clinical Endocrinology & Metabolism · 2018
    4. Hair Loss: Common Causes and Treatment PubMed · 2017
    5. Hirsutism: An Evidence-Based Treatment Update American Journal of Clinical Dermatology · 2014
    6. Epidemiology, Diagnosis, and Management of Polycystic Ovary Syndrome Clinical epidemiology · 2013
    7. Epidemiology, Diagnosis, and Management of Hirsutism: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome Society Human reproduction update · 2011
    8. The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report Fertility and Sterility · 2008
    9. Gender Differences in Mouse Skin Morphology and Specific Effects of Sex Steroids and Dehydroepiandrosterone Journal of Investigative Dermatology · 2005
    10. Role of Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate for the Maintenance of Axillary Hair in Women Hormone and Metabolic Research · 1993

    Related research 4

    1. Correlation of Clinical and Biochemical Hyperandrogenism in Thai Women with Polycystic Ovary Syndrome Journal of Obstetrics and Gynaecology Research · 2016
    2. Hyperandrogenism in Women: Polycystic Ovary Syndrome Hanyang Medical Reviews · 2012
    3. Polycystic Ovary Syndrome and Acne Skin therapy letter · 2011
    4. Diagnosis of Hyperandrogenism: Clinical Criteria Best Practice & Research Clinical Endocrinology & Metabolism · 2006