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Stem cell self-renewal is complex and needs more research for full understanding.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.

Dogs could be good models for studying human hair growth and hair loss.

Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Improving the environment and cell interactions is key for creating human hair in the lab.

Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.

Wnt signaling is crucial for skin development and hair growth.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.

Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.

Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Stem cells can help other stem cells by producing supportive factors.

Some skin tumors may start from hair follicle stem cells.

Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.

Type 1 Diabetes prevents hair growth by causing cell death in hair follicles.

Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.

The exact identity of skin stem cells and how skin cells differentiate is not fully known.

Different small areas within hair follicles send specific signals that control what type of cells stem cells become.