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research Laser on Hair Regrowth
This review explores clinical studies on low-level laser therapy (LLLT) for alopecia and suggests it may benefit patients unresponsive to conventional treatments, but larger studies are needed to confirm efficacy.
research A flexible fixed-sequence testing method for hierarchically ordered correlated multiple endpoints in clinical trials
This study introduces an extended approach to the Bonferroni procedure that accounts for correlations among endpoints, aiming to improve test power while maintaining strong control of the family-wise type I error rate in clinical trials.
research Lucio Phenomenon: Sequelae of Neglected Leprosy
This case study reported a rare occurrence of lepromatous leprosy with Lucio phenomenon in a 50-year-old Indonesian living in Malaysia, highlighting the necessity for primary care practitioners, even in non-endemic areas, to recognize this serious leprosy reaction to prevent complications and transmission.
research Frontal fibrosing alopecia associated with cutaneous lichen planus in a premenopausal woman
This case report describes the first known instance of fibrosing alopecia associated with cutaneous lichen planus, suggesting fibrosing alopecia may be a variant of lichen planopilaris.
research Morbihan disease and extrafacial lupus miliaris disseminatus faceie: a case report
This case report describes a rare concurrence of Morbihan disease with eyelid edema and extrafacial lupus miliaris disseminatus faciei in a patient, noting improvement of truncal lesions with roxithromycin and resolution of eyelid edema following surgical treatment.
research An engineered ferritin nanocage co-delivery system for targeted hair cells protection and hearing loss attenuation
This study developed a novel ferritin-based delivery system (LR@Fn) that effectively co-delivers RG108 and LLY283 for hearing loss treatment in animal models, reducing hair cell loss and synaptic damage more effectively than dexamethasone.
research Analysis of the FGF gene family provides insights into aquatic adaptation in cetaceans
This study found that cetaceans have adapted their fibroblast growth factors to assist in low bone density, hypoxia tolerance, and the development of rigid flippers, reflecting significant evolutionary changes for aquatic life.
research Progressive Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) from a Young Age Due to a Rare Genetic Disorder, Familial Partial Lipodystrophy: A Case Report and Review of the Literature
This case report highlights a female patient with familial partial lipodystrophy who showed significant improvement in liver stiffness after starting leptin replacement therapy.
research Graham‐Little Piccardi Lassueur syndrome and review of the literature
This case report documents the first known instance of Graham‐Little Piccardi Lassueur Syndrome in Saudi Arabia, observed in an adult dark-skinned male.
research Successful outcome of follicular unit extraction in a patient with alopecia due to Hansen’s disease
Follicular unit extraction successfully restored hair growth in a leprosy patient without disease relapse.
research CRISPR/Cas9‐mediated loss of FGF5 function increases wool staple length in sheep
This study found that CRISPR/Cas9-induced loss-of-function mutations in the FGF5 gene significantly increased wool length and yield in genetically modified Chinese Merino sheep compared to wild-type controls.
research Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves’ ophthalmopathy
This study found that PD-MSCs overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by modulating key signaling pathways, suggesting a novel therapeutic approach for degenerative diseases.
research Follicular Unit Plain Speak
This abstract introduces the concept of follicular units (FUs) in the human scalp but presents no new research findings.
research Linear and Annular Lupus Panniculitis of the Scalp with Annular Lupus Panniculitis of the Face in a Child
In this case report, a 4-year-old Indian girl with linear and annular lupus panniculitis of the scalp achieved complete remission and hair regrowth with oral corticosteroids, showing no relapse after 6 months of follow-up.
research Ectopic expression of FGF5s induces wool growth in Chinese merino sheep
This study found that ectopic expression of FGF5s in transgenic Chinese Merino sheep increased wool length and greasy fleece weight compared to non-transgenic controls.
research LP-161 Tjalma syndrome (Pseudo-Pseudo Meigs Syndrome): polyserositis with increased CA-125 in patients with systemic lupus erythematosus
This case report highlights that Tjalma Syndrome may present as a main symptom of systemic lupus erythematosus and should be considered in patients with ascites, pleural effusions, and elevated CA-125 levels.
research Occipital Fibrosing Alopecia in a Young Male: A Case Report
This discussion highlights the evolving clinical spectrum of lichen planopilaris, noting atypical features and presentations in younger males that suggest potential different pathomechanisms from previously recognized variants.
research Discoid lupus alopecia complicated by frontal fibrosing alopecia on a background of androgenetic alopecia
Woman has discoid lupus, frontal fibrosing, and androgenetic alopecia.
research PT4:07 Anifrolumab as rescue therapy in life-threatening, infection-complicated SLE: a biomarker-guided case beyond trial criteria
This case report describes how anifrolumab, used beyond trial-eligible populations, led to significant clinical and serological recovery in a 45-year-old woman with organ-threatening systemic lupus erythematosus complicated by infection and resistant to conventional treatments like cyclophosphamide and rituximab.
research GP85 The irish experience in paediatric parry romberg syndrome- a case series highlighting management and surgical outcomes
This case series reports favorable outcomes for children with Parry Romberg Syndrome who underwent facial fat-grafting, showing it as a safe and well-tolerated procedure with no complications or relapses observed.
research Constitutive Internalization of the Leucine-rich G Protein-coupled Receptor-5 (LGR5) to the Trans-Golgi Network
This study identifies specific molecular components involved in the intracellular trafficking of LGR5, revealing mechanisms that differ from typical GPCR recycling processes.
research LGR5 is a Conserved Marker of Hair Follicle Stem Cells Across Species and is Present Early and Throughout Follicle Morphogenesis
This study demonstrated that LGR5 is a marker of hair follicle stem cells across species using a transgenic pig model and noted similarities and differences in expression patterns compared to humans.
research 231 Novel protocol for the invitro maintenance and expansion of adult epidermal LGR5+ stem cells
This study found that mouse embryonic fibroblasts better supported the growth and maintenance of LGR5+ epidermal stem cells compared to porcine fetal fibroblasts, under various culture conditions.
research Lichen planus pigmentosus and lichen planopilaris
This review discusses the potential relationship between lichen planus pigmentosus and frontal fibrosing alopecia, presenting a case study but reporting no new clinical findings.
research Laser Lax for Donor Closure
Laser Lax is a new tool that measures scalp looseness accurately and comfortably.
research Living with the wolf
This article narrates the author's personal journey with systemic lupus erythematosus over 15 years, highlighting the challenges and strategies for managing this complex disease and maintaining quality of life.
research Efficay of platelet rich plsama in conjunct with photobiomodulation by low level laser therapy versus platelet rich plasma in androgenic alopecia
This study conducted a comparative analysis of platelet rich plasma and low level laser therapy for androgenetic alopecia but does not present new clinical findings.
research Hair Loss in Lichen Planopilaris and Frontal Fibrosing Alopecia: Not Always Irreversible
This case report presents two instances where typically irreversible lichen planopilaris and frontal fibrosing alopecia showed signs of hair regrowth and symptom improvement following specific treatments.
research NEW CHALLENGE TO CANCER AND LONGEVITY
This article discusses the potential benefits of GcMAF and oral MAF, developed by "Saisei Mirai", for cancer and other conditions, but reports no new clinical results.