Lichen Planus Pigmentosus and Lichen Planopilaris

    January 2016 in “ Dermatology online journal ”
    Gabriela Cobos, Randie H. Kim, Shane A Meehan, Nada Elbuluk
    TLDR Some people with lichen planus pigmentosus might later develop frontal fibrosing alopecia.
    The document discussed a case of lichen planus pigmentosus (LPPi) and lichen planopilaris (LPP), two variants of lichen planus, an inflammatory skin condition. The patient exhibited dark-brown-to-grey macules and patches on the upper extremities, neck, and face, along with a recessed hairline and decreased hair density on the scalp. Laboratory tests showed elevated prolactin levels, while other antibodies were negative. Histopathology revealed a decreased number of terminal anagen follicles, sparse perifollicular lymphocytic infiltrate, and perifollicular fibrosis. LPPi, first described in Indian patients in 1974, predominantly affects darker-skinned individuals and presents with asymptomatic pigmentation in sun-exposed areas. The etiology is unknown, but potential triggers include viral infections, impaired carbohydrate metabolism, drugs, topical agents, and sun exposure.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 37 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I've tried everything and my hair is still thinning

      in Chat  6 upvotes 9 months ago
      The user has tried finasteride, oral minoxidil, iron supplements, vitamin D, and vitamin B12, but their hair is still thinning after 5 years. Another user suggested trying dutasteride.

      community Clascoterone (Winlevi) Update for Canada

      in Treatment  16 upvotes 2 years ago
      Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 2 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

    Related Research

    1 / 1 results