TLDR A young man with an unusual type of scarring hair loss suggests a possible new variant of a known scalp condition.
The document described an unusual case of fibrosing alopecia in a 26-year-old Caucasian male, who exhibited scarring alopecia on the occipital scalp, diverging from the common frontotemporal presentation in postmenopausal women. The patient, who had a history of androgenetic alopecia and scalp folliculitis, was diagnosed with a Lichen planopilaris (LPP)-spectrum disorder through trichoscopy and biopsy. The case underscores the importance of recognizing atypical manifestations of fibrosing alopecia, suggesting a potential new clinical variant within the LPP spectrum. Treatment with topical clobetasol and oral hydroxychloroquine resulted in a partial response after 6 months, and the document calls attention to the diagnostic challenges of atypical LPP variants, leaving open the question of whether this represents a new entity within the disorder spectrum.
48 citations,
November 2018 in “Journal of dermatological treatment” Women are more likely to have Lichen planopilaris, and treatments with cyclosporine and methotrexate are most effective but less safe than mycophenolate mofetil.
15 citations,
December 2017 in “Journal of The European Academy of Dermatology and Venereology” Frontal fibrosing alopecia and androgenetic alopecia may be related, with a possible shared cause.
41 citations,
July 2017 in “Journal of The American Academy of Dermatology” Men with Frontal fibrosing alopecia typically lose hair on the front scalp and sometimes on sideburns and upper lip, with treatments showing varied success.
8 citations,
October 2016 in “Actas Dermo-Sifiliográficas” FFA in men, often mistaken for other hair loss types, may be more common than thought and needs larger studies for confirmation.
26 citations,
August 2016 in “Actas Dermo-Sifiliográficas” Frontal Fibrosing Alopecia in men is often missed and can come with symptoms like facial bumps and hair loss on eyebrows and limbs.
27 citations,
January 2015 in “Current problems in dermatology” The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.
28 citations,
September 1998 in “Medical Clinics of North America” Most hair loss can be diagnosed with patient history and physical exam, and a few common types make up most cases.
5 citations,
October 1988 in “Clinics in Dermatology” Minoxidil promotes hair growth but exact mechanism is unknown.