May 2026 in “Scholars Journal of Medical Case Reports” In this report, researchers described a 36-year-old woman with frontal fibrosing alopecia resistant to standard treatments, who showed significant improvement after six months on a combination of intralesional betamethasone and oral hydroxychloroquine, suggesting potential benefits of this therapy approach in managing the condition.
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May 2009 in “Pediatric Dermatology” This case report describes a 5-year-old girl with childhood discoid lupus erythematosus, where treatment led to reversal of scarring alopecia and hair regrowth.
January 2021 in “International journal of basic and clinical pharmacology” This study found that hydroxychloroquine was less effective than betamethasone oral mini pulse therapy in managing alopecia areata, with patients on hydroxychloroquine experiencing score increases and more relapses at 24 weeks, though adverse event rates were similar between the groups.
This study found that while hydroxychloroquine was effective and safe for treating alopecia areata, patients using it experienced more relapses compared to those receiving betamethasone.
July 2022 in “British Journal of Dermatology”