research Impairment of Notch 1 Signaling Is a Common Defect in Lesions From Patients With Hidradenitis Suppurativa
Notch1 signaling is impaired in hidradenitis suppurativa, affecting skin and hair cells.
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research Targeting Anti-Inflammatory Immunonanocarriers to Human and Murine Neutrophils via Ly6 Antigen for Psoriasiform Dermatitis Alleviation
The study created special nanoparticles that effectively deliver an anti-inflammatory drug to treat skin inflammation in psoriasis.
research Comparative Efficacy of Topical Anthralin and Intralesional Triamcinolone in the Treatment of Alopecia Areata
Triamcinolone regrows hair better but relapses more than anthralin.
research High Throughput T Cell Receptor Sequencing Identifies Clonally Expanded CD8+ T Cell Populations in Alopecia Areata
Expanded CD8+ T cells are linked to Alopecia Areata and may cause relapse after treatment.
research Tolerance and Efficacy of a New Emollient Barrier Cream in Pediatric and Adult Population with Mild to Moderate Atopic Dermatitis
The new cream is safe and effective for mild to moderate atopic dermatitis.
research Impaired Follicular Nrf2 Signaling: Potential Early Therapeutic Target in Hidradenitis Suppurativa
Targeting impaired Nrf2 signaling might help treat hidradenitis suppurativa early on.
research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
research Inflammatory Role of Sex Steroids in Hidradenitis Suppurativa: An Androgenic Phenotype
Sex hormones may be linked to inflammation in Hidradenitis Suppurativa.
research Evaluation of Cardiovascular Disease Risk Factors in Patients with Mycosis Fungoides
Patients with mycosis fungoides have a higher risk of heart disease.
research Gamma Delta T Cells as Novel Players in Alopecia Areata Pathobiology: Vdelta1 Positive T Lymphocytes May Recognize Stressed Hair Follicle Keratinocytes, Leading to IFN Gamma-Dependent Hair Follicle Dystrophy and Immune Privilege Collapse
Targeting specific T cells may help treat alopecia areata.
research The Potential Role of Acetylcholine Receptors in Acne Inversa Pathogenesis
Acetylcholine receptors might be involved in the development of acne inversa and smoking could worsen the condition.
research IL-15 Prolongs Hair Growth and Acts as a Guardian of Human Hair Follicle Immune Privilege
IL-15 helps maintain hair growth and protects the immune status of hair follicles.
research Plasmacytoid Dendritic Cells as a Key Player in the Initiation Phase of Alopecia Areata-Induced C3H/HeJ Mouse
Plasmacytoid dendritic cells, which overproduce IFN-α, may play a crucial role in starting alopecia areata, an autoimmune disease causing hair loss.
research SnapshotDx Quiz: September 2016
Scalp psoriasis features reversible hair loss and specific immune activation, with no significant hair follicle damage.
research Functional Analysis of the Stratum Corneum of Scalp Skin: Studies in Patients with Alopecia Areata and Androgenetic Alopecia
Scalp skin barrier affects hair loss; personalized treatments needed.
research Clinical and Biological Impact of the Exposome on the Skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
research MicroRNA in Skin Diseases
Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Skin and Glucocorticoids: Effects of Local Skin Glucocorticoid Impairment on Skin Homeostasis
Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.
research Heme Oxygenase and the Skin in Health and Disease
HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
research Cell Death as an Architect of Adult Skin Stem Cell Niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research A Multicomponent Skin-Targeted COVID-19 Vaccine Elicits Robust Humoral and Cellular Immune Responses
The new skin-targeted COVID-19 vaccine creates strong immune responses and could improve vaccination methods.
research Mechanisms Regulating Skin Immunity and Inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research The Role of Tight Junctions in Skin Barrier Function and Dermal Absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
research Targeting the Janus Kinase Family in Autoimmune Skin Diseases
Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
research Cell Death in the Skin: Mechanisms and Implications
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Smoking and the Skin: Effects and Therapeutic Potential
Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
research Human αβ and γδ T Cells in Skin Immunity and Disease
Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
research The Endocannabinoid System of the Skin: A Potential Approach for the Treatment of Skin Disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Regulatory T Cells in Inflammatory Skin Disease: From Mice to Humans
Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.