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This review discusses the role of leptin in skin biology and pathology, highlighting its potential in enhancing skin regeneration, hair cycle progression, and wound healing, but reports no new clinical results.

This study found that leptin acts as an inducer of the anagen phase in hair follicles, suggesting its role as a potential player in hair biology.

This study found that human follicular papilla cells in the scalp produce leptin and express functional leptin receptors, suggesting leptin's significant role in hair biology.

This study found that leptin from dermal white adipose tissue may regulate hair growth and cycle progression through its receptor on hair follicle epithelium in mice and humans.

Leptin helps start the growth phase of hair.

In this study, HIIT increased adiponectin levels and improved cholesterol profiles in women with PCOS, but did not change leptin or vaspin levels.

This study found that in bovine skin, leptin and its receptor are expressed in the epidermis and hair follicles, suggesting a role in epidermis growth and hair follicle cycling through paracrine and autocrine mechanisms.

In this study, isotretinoin treatment for acne vulgaris significantly increased serum adiponectin and leptin levels but had no significant effect on BMI or ghrelin levels.

This review explores the current understanding of leptin's role in psoriasis and other skin diseases but reports no new clinical findings, emphasizing that the exact mechanisms of its impact are still being investigated.

This review discusses leptin's regulatory roles in the progression of various dermatological diseases and reports no new clinical results, highlighting a complex relationship still under investigation.

This case study reported a rare occurrence of lepromatous leprosy with Lucio phenomenon in a 50-year-old Indonesian living in Malaysia, highlighting the necessity for primary care practitioners, even in non-endemic areas, to recognize this serious leprosy reaction to prevent complications and transmission.

This study found that both ethanol and aqueous extracts of Lepidium sativum seeds improved insulin signaling and reduced obesity-related metabolic changes in high-fat diet-fed rats, suggesting potential as a dietary supplement.

This case report describes a instance of lepromatous leprosy in a renal transplant recipient, highlighting the potential for leprosy in immunocompromised patients and emphasizing the importance of including it in differential diagnoses for unusual skin lesions.

This case report describes a 5-day-old male infant with a constellation of symptoms, including leptomeningeal angiomatosis, hair follicle nevus, and congenital alopecia, potentially representing a novel neurocutaneous syndrome.

This review discusses mechanisms of wound healing impairment in leptin-deficient murine models used for diabetic research, and reports no new clinical results; the authors emphasize the need for further study.

This article discusses the various techniques for eyebrow replacement and concludes that punch grafting is specifically recommended for restoring hair to the medial end after vascular island transfer.

This study found that men with androgenetic alopecia had significantly higher plasma leptin levels, which were associated with an increased risk of developing the condition.

This case report describes a 29-year-old Japanese-Paraguayan man who experienced a relapse of leprosy 14 years after initial treatment, presenting with severe pain and skin lesions but no sensory impairment.

This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.

This report describes a rare case of leprosy involving the scalp, a location not typically conducive to Mycobacterium leprae infection, and adds to existing literature without presenting new experimental findings.

This study found that adipokines were expressed in the epidermis, hair follicles, sebocytes, apocrine glands, and vascular endothelium of normal canine skin, but not in the dermis or hypodermis.

This case study suggests that low leptin levels in obese hyperandrogenic postmenopausal women might indicate the presence of androgen-secreting tumors.

This pilot study found elevated levels of leptin and other proinflammatory molecules in the serum of melanoma patients, suggesting a potential role for leptin in melanoma progression and a possibility for targeting it in adjuvant therapy.

This report describes a rare case of leprotic alopecia in a 26-year-old female, secondary to paucibacillary leprosy, with a clinical picture mimicking alopecia areata-vitiligo overlap syndrome.

This case report documents a rare instance of a female Indian patient with borderline-lepromatous leprosy experiencing generalized leprous alopecia of the scalp and lepromatous lymphadenitis of the suboccipital node.

This article explores the correlation between alopecia leprotica and Buddhist customs, presenting evidence that leprosy is contracted during infancy or childhood rather than in maturity; it reports no new clinical findings.

In this study, high doses of Lepidium sativum seeds extract were reported to cause toxicity and tissue damage in animals, suggesting the need for careful use under medical supervision.

This study reports that patients with specific MFN2 mutations, including p.Arg707Trp, exhibit significant upper body fat overgrowth with suppressed leptin production, suggesting tissue-selective mitochondrial dysfunction and potential therapeutic targets.

Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.

PLAU and SerpinB2 affect cell death differently in various forms of leprosy and could be targets for new treatments.