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This study found that intravenous administration of a shark-derived receptor antibody, 3P17, promoted hair growth in mice by increasing hair matrix cell proliferation and activating leptin-STAT3 signaling, with transdermal leptin delivery enhancing this effect through improved skin penetration.

In this case study, a 20-year-old male with alopecia areata achieved successful hair regrowth across all patches and experienced no recurrence after Ayurvedic treatment, which included interventions such as Shodhana, Shamana, and Pracchanna Karma.

This study found that patients with alopecia areata had lower adiponectin levels and higher leptin levels compared to healthy controls, with leptin levels correlating positively with insulin resistance markers and negatively with HDL cholesterol.

This review discusses how metaphorical language in dermatology, particularly terms like "butterfly" and "moth," aids in diagnosing and understanding skin conditions by highlighting their distinctive clinical presentations and underlying pathophysiology.

This study found that curcumin supplementation in adults significantly increased serum adiponectin levels and decreased leptin levels, based on a meta-analysis of 13 randomized controlled trials.

In this single case study, Ayurvedic treatments using Madhuka taila nasya and Japaakusumadi lepa were reported to benefit a patient with premature hair graying, suggesting a potential safe and effective alternative to conventional methods.

This study discusses how historical misconceptions conflated leprosy and psoriasis, leading to widespread social stigma for psoriasis patients, and highlights key figures like Robert Willan and Ferdinand von Hebra who advanced understanding by ultimately separating the two diseases in medical classification.

This study found that Lepidium sativum seed extract showed potential in treating alopecia in rats by reducing 5(alpha)-dihydrotestosterone levels and improving hair length compared to minoxidil.

This study reports a case of Indralupta (Alopecia Areata) successfully treated using Ayurvedic methods including Prachhan karma, Lepa, and Shirodhara, offering an alternative to conventional treatments like minoxidil and steroids, which may have adverse effects.

This study found that COVID-19 pandemic restrictions may have led to delayed access to dermatological care for leprosy patients, resulting in increased bacillary load and disease severity.

In this source, a case of a female patient with indralupta (alopecia areata) was successfully treated using Ayurvedic methods, specifically jaluaka, haridra, and nimbalepa, suggesting an effective alternative to corticosteroids, which have harmful side effects and are unsuitable for long-term use.

This case report describes a patient with untreated lepromatous leprosy developing Lucio's phenomenon, highlighting difficulties in distinguishing it from erythema nodosum leprosum with vasculonecrotic lesions.

This study reports the first known occurrence of Leporacarus gibbus infestation alongside Cheyletiella parasitovorax and Psoropotes cuniculi in a domestic rabbit in Espírito Santo, Brazil.

This study suggests that specific mutations in the MFN2 gene, including the p.Arg707Trp allele, can result in tissue-selective mitochondrial dysfunction leading to excessive upper body fat growth and low leptin levels.

In this study, PSA levels were significantly lower among African-American men with higher C-peptide levels and Caucasian men with higher HbA1c levels, suggesting a link between metabolic markers and prostate cancer detection.

This study identified significant differences in cytokine levels between people with primary cicatricial alopecias and unaffected individuals, suggesting cytokines may play a role in the condition's autoimmune nature and management.

In this study, higher plasma leptin levels were associated with increased risk and severity of androgenetic alopecia in men, but further research is needed to understand the clinical implications.

This study found that in people with leprosy sequelae, ulcers on the lower limbs exhibited decreased microbial diversity and reduced abundance of specific bacteria compared to normal skin, with skin metabolites closely linked to these microbial changes.

This study reviewed the pharmacological properties of Priyaladi lepa, an Ayurvedic formulation, and reported its potential anti-dandruff benefits due to anti-inflammatory, anti-fungal, anti-microbial, anti-pruritic, antioxidant, and exfoliation effects, warranting further research for managing Darunaka (dandruff).

This case report describes a woman in her 30s diagnosed with systemic lupus erythematosus, characterized by alopecia, arthritis, photosensitivity, and skin rashes, confirmed through positive serology.

This study explored the use of Kasisadi Lepa, a classical herbo-mineral formulation, and found its components could reduce dandruff by addressing scalp inflammation, microbial growth, and tissue damage with potential integration into long-term scalp health strategies.

This study compared two Ayurvedic treatments for alopecia and found that applying Chirabilwa Lepa after Prachanna led to significantly better improvement in hair regrowth than using Gunja Lepa after Prachanna among the 60 patients studied.

In this clinical study, Prachhanna followed by Guñjā lepa was found to be more effective than PRP therapy with Minoxidil 5% in improving hair regrowth and reducing symptoms in patients with Indralupta (Alopecia Areata), achieving 91.14% overall improvement compared to 74.74% for the alternative treatment.

This study observed that Prachhanna followed by Guñjā lepa was more effective than Platelet-Rich Plasma therapy with Minoxidil 5% in promoting hair regrowth and reducing symptoms of Indralupta, showing greater reductions in hair loss and itching over a 45-day period.

This review discusses the use of Kusthadi Lepam for treating Ek-Kustha, which resembles psoriasis, but reports no new clinical results; the authors suggest further research on its efficacy and safety.

This review examines Ayurvedic and modern literature on combining Anu Taila Nasya and Gokshura lepa for hair loss and presents no new clinical results.

In this study, researchers reported significant improvements in hair follicle diameter, thickness, and reduced hair root gap after treating male pattern hair loss with a regimen of Prachanna, Chitrakadi lepa, and Jeevamrutham lehyam over four months.

This case study on a 24-year-old male with Indraluptha (patchy hair loss) found that two cupping sessions followed by the application of Gunjapahala Lepa promoted new hair follicle growth and reduced lesion areas.

This study aims to evaluate the efficacy of a treatment approach called Sthanika Chikitsa, involving Shiro Lepa and specific herbal and nasal preparations, for managing Indralupta, a condition akin to Alopecia Areata characterized by hair loss. Results are not provided in the abstract.

In this study of 52 patients with Indralupta, both Asthisrinkala lepa and Triphala mashi lepa showed a highly significant reduction in lesion size post-Pracchanna treatment, with Asthisrinkala lepa proving more effective compared to Triphala mashi lepa.