A Randomized Open Labelled Comparative Clinical Study to Evaluate the Efficacy of Prachhanna Followed by Gunja Lepa and PRP Therapy Followed by Application of Minoxidil Solution in the Management of Indralupta with Special Reference to Alopecia Areata - A Comparative Clinical Study

This clinical study compared the efficacy of two treatments for Indralupta, an Ayurvedic condition similar to alopecia areata, in 40 patients over 45 days. Group A received Prachhanna karma followed by Guñjā lepa, while Group B received Platelet-Rich Plasma (PRP) therapy with topical Minoxidil 5%. Group A demonstrated superior results, with hair loss reduction of 36.0% by Day 15, 76.0% by Day 30, and 88.0% by Day 45, and itching relief of 40.0%, 77.1%, and 94.3% at the same intervals. Group B showed less improvement, with hair loss reduction of 16.0%, 52.0%, and 68.0%, and itching relief of 22.2%, 55.6%, and 81.5%. Overall improvement was 91.14% in Group A compared to 74.74% in Group B. The study concludes that Prachhanna followed by Guñjā lepa is more effective, addressing both Dosha imbalance and follicular regeneration.