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GlossaryClofazimine

antibiotic used to treat leprosy by inhibiting bacterial growth

Clofazimine is an antibiotic primarily used to treat leprosy, a chronic infectious disease caused by Mycobacterium leprae. It works by binding to the DNA of the bacteria, inhibiting their growth and reducing inflammation. While it is effective in managing leprosy, it can cause side effects such as skin discoloration and gastrointestinal issues.

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research BCG'osis

2 citations , February 1981 in “Journal of the Royal Society of Medicine”

A three-year-old girl survived a rare serious infection caused by BCG vaccination, which improved after treatment with a leprosy drug.

research Cortexolone 17a-Propionate: Preclinical Profile of a New Topical, Skin Selective, Steroidal Antiandrogen

April 2012 in “Journal of the American Academy of Dermatology”

Clofazimine may be effective for treating ashy dermatosis.

research Ashy Dermatosis: Treatment with Clofazimine

April 2012 in “Journal of the American Academy of Dermatology”

Clofazimine successfully treated a man's ashy dermatosis, clearing his skin lesions.

research Lupus Erythematosus: Considerations About Clinical, Cutaneous, and Therapeutic Aspects

15 citations , January 2014 in “Anais Brasileiros de Dermatologia”

Lupus treatment requires a combination of drugs and therapies, with research needed for new options.

research Cutaneous Lupus Erythematosus: A Comprehensive Review

74 citations , March 2001 in “Seminars in Cutaneous Medicine and Surgery”

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

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