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300-330 / 1000+ resultsresearch Alopecic Patches on the Extremities of a Young Man
This report describes a rare case of scarring alopecia, diagnosed as lichen planopilaris (LPP), affecting solely the limbs, highlighting the necessity for thorough evaluation of LPP beyond the scalp.
research Integrated Safety Analysis of Ritlecitinib for the Treatment of Alopecia Areata (AA) From the Phase 2 and Phase 3 ALLEGRO Clinical Trial Program
In this study, ritlecitinib, an oral JAK3/TEC inhibitor, was evaluated for safety in patients aged 12 and older with alopecia areata across four clinical trials up to 36 months, showing a safety profile with reported adverse events and lab abnormalities summarized per dosing groups.
research Long-term pubic dermatitis diagnosed as white piedra.
In this case report, a 58-year-old man's 30-year undiagnosed pruritic rash in the pubic area was successfully treated with topical ketoconazole after being identified as white piedra using a Wood lamp.
research Comparative study of the action of dynamized forms of melatonin and lissotriton
The study reported that mice receiving dynamized Melatonin 6 cH and Lissotriton 6 cH for 14 days exhibited improved coat health and increased endurance in forced swimming tests, with Melatonin-treated mice swimming 2.5 times longer and Lissotriton-treated mice 4 times longer than controls.
research A case of scarring alopecia
The woman was diagnosed with lichen planopilaris and can be treated with corticosteroids.
research [Studies on monilethrix].
This report describes four cases of monilethrix in children and concludes that periodic inhibition of keratin synthesis, not a metabolic defect, may explain the hair abnormality.
research COLOCALIZATION OF ALOPECIA AREATA AND LICHEN PLANUS
This article discusses the colocalization of alopecia areata and lichen planus in pediatric dermatology and does not present new clinical results.
research Current best evidence in pigmentary dermatology
In a randomized phase 2b clinical trial, oral ritlecitinib significantly reduced facial vitiligo area scores in patients with active nonsegmental vitiligo compared to placebo, with a favorable safety profile observed over 48 weeks, suggesting its potential as an effective treatment option (Ezzedine et al., 2023).
research Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, p2y5/LPA6
This study found that p2y5 functions as a novel LPA receptor involved in the G13-Rho signaling pathway, with implications for human hair growth, and proposes renaming it to LPA6.
research A SYNOPTIC REVIEW ON PRIYALADI LEPA: AN AYURVEDIC TOPICAL FORMULATION FOR THE MANAGEMENT OF DARUNAKA (DANDRUFF)
This study reviewed the pharmacological properties of Priyaladi lepa, an Ayurvedic formulation, and reported its potential anti-dandruff benefits due to anti-inflammatory, anti-fungal, anti-microbial, anti-pruritic, antioxidant, and exfoliation effects, warranting further research for managing Darunaka (dandruff).
research Lichen planopilaris associated with hair extensions in a patient with alopecia areata: A case report
Hair extensions can worsen scalp conditions and should be avoided in those with alopecia.
research Alopecia secondary to poly-L-lactic acid dermal fillers
In this study, researchers noted that while Poly-L-lactic acid dermal fillers boost collagen synthesis to add volume and reduce wrinkles, there is no established link between these fillers and hair loss according to existing literature.
research Monilethrix with Acitretin
This report describes a 7-year-old girl with monilethrix who showed significant improvement while on acitretin treatment, but symptoms returned after stopping the medication.
research Uncommon Presentation of Pityriasis Rubra Pilaris of the Scalp: Clinical, Trichoscopic, and Histopathologic Features and Review of the Literature
This case report details a unique instance of pityriasis rubra pilaris affecting only the scalp, highlighting novel trichoscopic features and emphasizing the importance of recognizing this rare presentation for improved diagnosis and treatment.
research A Case of Kerion Celsi Caused by Microsporum gypseum (Arthroderma gypseum ) in a Child
This case report details a 10-year-old boy diagnosed with kerion celsi caused by Microsporum gypseum, successfully treated with itraconazole over 4.5 months.
research Efficacy and Safety of Switching from Baricitinib to Ritlecitinib in Severe Alopecia Areata
In this study, researchers found that ritlecitinib, a JAK3/TEC inhibitor, significantly improves hair regrowth, quality of life, and psychological well-being in patients with severe alopecia areata who had inadequate or no response to baricitinib, a JAK1/2 inhibitor.
research Asymmetric adhesive SIS-based wound dressings for therapeutically targeting wound repair
This research reported that a newly developed adhesive wound dressing (SIS/PAA/LAP) demonstrated higher tissue adhesion and burst strength compared to conventional products, and improved tissue repair outcomes in animal models, suggesting potential for enhanced wound healing applications.
research Formulasi Sediaan Losio Ekstrak Etanol Meniran (Phyllanthus niruri L.) Sebagai Penumbuh Rambut Terhadap Tikus Putih (Rattus norvegicus) Jantan Galur Wistar
This study found that lotion containing ethanolic extract of Phyllanthus niruri and 1% menthol enhanced hair growth in white Wistar rats more than a formula without menthol, although not significantly.
research How to manage an 18-20 year old with hair loss that is not improved with ketoconazole?
Ritlecitinib may help young adults with severe alopecia areata when ketoconazole fails.
research Treatment of Lichen Planopilaris With Abrocitinib
This case report by the researchers observed a complete remission of lichen planopilaris in a 58-year-old woman after treatment with the JAK-1 inhibitor abrocitinib, although they noted that concurrent topical therapy might have contributed to this outcome.
research New Topical Treatment for Psoriasis
In this case report, a 47-year-old man with extensive psoriasis saw significant improvement in scaling and itching after using a new lotion containing clobetasol and other ingredients for one week, but further research is needed to confirm these findings.
research Formulation and Evaluation of Herbal Liquid Shampoo
In this study, researchers developed an herbal liquid shampoo using ingredients like shikekai and tulsi powder, aiming for safety and efficacy without the damaging effects of chemical alternatives, and found that it could clear dandruff and dirt while enhancing hair strength and growth.
research TYK2 Inhibition with Deucravacitinib Improves Clinical Outcomes and Resolves Interferon-Driven Inflammation in Lichen Planopilaris
In this clinical trial, patients with lichen planopilaris treated with the oral TYK2 inhibitor deucravacitinib showed significant improvement in PGA, LPPAI, and Skindex-16 scores over 24 weeks, with transcriptomic analyses indicating decreased inflammatory and immune pathway activity post-treatment.
research Ritlecitinib: Efficacy of a Novel Therapy for Severe Alopecia Areata in Patients Aged 12 Years and Older
This review analyzes the mechanism and evidence supporting the approved use of ritlecitinib, a JAK3/TEC kinase inhibitor, for treating severe alopecia areata in patients aged 12 and older, highlighting its role in the changing therapeutic landscape of this immune-mediated disease.
research SAT-369 Marine-Lenhart Syndrome: Case Report
This case report documented the management of a 46-year-old female with Marine-Lenhart syndrome, combining antithyroids with minimally invasive sclerotherapy to achieve euthyroidism and reduce thyroid nodule size by 58%.
research POLEVAN®—A Multifunctional Natural Hair Ingredient, as Determined by In-Vitro and Human Studies
This study evaluated a levan-based polysaccharide, POLEVAN®, in shampoo formulations and reported that it significantly increased hair glossiness by 24%, allowed a reduction of surfactant content by up to 50% without affecting foam, and maintained scalp moisturization similar to hyaluronic acid in a clinical setting.
research The Double-Edged Sword of Epidermal Growth Factor Receptor Inhibitor: Rash as Toxicity and Prognostic Marker
In this reported case, a 50-year-old man developed an acneiform rash, a common skin side effect of EGFR inhibitor therapy, after starting lapatinib for breast cancer; treatment with doxycycline and hydrocortisone cream led to significant improvement within one week.
research Line‐field confocal optical coherence tomography: A new diagnostic method of lichen planopilaris
This study found that line-field confocal optical coherence tomography effectively visualized key diagnostic features of classic lichen planopilaris in real time, suggesting its potential as a valuable diagnostic tool.
research The effects of fulvic acids and low-level laser therapy on orthodontic retention in rats
This study found that low-level laser therapy effectively reduced relapse rates, while functional appliances did not; combining them offered no additional benefits.