101 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports the successful differentiation of mouse induced pluripotent stem cells into keratinocytes that can regenerate skin and its structures in an in vivo environment.
65 citations
,
August 2013 in “Acta Biomaterialia” This study suggests that a novel micropatterned dermal–epidermal matrix (μDERM) enhances keratinocyte function and epidermal morphology, offering potential improvements in skin substitute design for wound healing applications.
63 citations
,
September 2009 in “Regenerative Medicine” This study developed a method for expanding human dermal papilla cells in vitro while maintaining their ability to induce hair growth, advancing the potential for follicular cell implantation as a treatment for hair loss.
43 citations
,
August 2008 in “Regenerative Medicine” In this study, murine follicular cell aggregates developed into hair-like structures in culture, which upon implantation into mice skin matured into complete hair follicles, suggesting potential for treating hair loss.
26 citations
,
February 2012 in “Journal of Investigative Dermatology” This study found that dermal papilla cells from human hair follicles can be reprogrammed into induced pluripotent stem cells, but their efficiency is similar to that of fibroblasts, unlike in mice.
11 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This review discusses the history and challenges of hair follicle regeneration using follicular fragments and dissociated cells, without presenting new clinical results.
4 citations
,
November 2021 in “Frontiers in Cell and Developmental Biology” Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.
1 citations
,
July 2025 in “The Open Dermatology Journal” This study explores the transformative role of tissue engineering in cosmetics, highlighting innovations like lab-grown skin and personalized grafts that enhance product efficacy, offer ethical alternatives to animal testing, and address aesthetic issues such as scarring and aging.
February 2024 in “Tissue & Cell” This review evaluates recent advancements in hair follicle bioengineering and discusses the potential for developing effective treatments for hair loss through tissue engineering, despite current challenges in creating functional cultured human hair cells.
November 2015 in “Hair transplant forum international” Early attempts at using cloned cells for hair transplants failed, but 3D cell growth showed some promise.
7 citations
,
November 2020 in “Experimental Dermatology” This article reviews skin regeneration and fibrosis, identifying key cellular and molecular players, and emphasizing the potential to manipulate the postwound environment to promote regeneration over fibrosis.
December 2023 in “Scientific reports” This study assessed three lactic acid bacteria-fermented proteins and found that F-WPI and F-SPI could normalize osteoclastogenesis markers in vitro, while F-SPI enhanced osteoblastogenesis markers, suggesting potential as dietary supplements for osteoporosis prevention, though further research into mechanisms is needed.
8 citations
,
October 2020 in “Pharmaceutics” This study explored using a chitosan oligomer coating for topical delivery of dutasteride-loaded nanostructured lipid carriers, aiming to reduce systemic exposure and cytotoxicity.
14 citations
,
January 2012 in “International Journal of Trichology” This case report highlights the importance of suspecting underlying malignancy, such as Hodgkin's lymphoma, in patients with diffuse hair loss and other cutaneous symptoms.
4 citations
,
September 2020 in “Stem Cell Research & Therapy” In this study, xenobiotic-free human multipotent adult progenitor cells were found to improve wound vascularization and healing in mice, suggesting potential applicability for clinical use in humans.
39 citations
,
June 2017 in “Scientific Reports” Different lab conditions and light treatment methods change how human skin cells respond to light therapy.
January 2024 in “Wiadomości Lekarskie” In this retrospective study conducted at Grodno Regional Children's Hospital, researchers found that children in western Belarus showed more severe COVID-19 symptoms in 2021 compared to 2020, with urban children primarily affected, and family contact emerging as the most common source of infection.
28 citations
,
March 2010 in “Histochemistry and cell biology” Skin cells can help create early hair-like structures in lab cultures.
6 citations
,
April 2021 in “Scientific Reports” This study found that Phytochrome A is crucial for regulating central metabolism and the transition to mature seedling proteomes in tomato seedlings grown under far-red light.
13 citations
,
August 2007 in “Journal of Investigative Dermatology” Mouse hair can regrow in a special lab setup without serum.
27 citations
,
April 2023 in “Pharmaceuticals” In this review, Ziziphus lotus was reported to have multiple traditional uses and demonstrated various pharmacological properties in lab and animal studies, with over 181 identified bioactive compounds; however, clinical trials are needed to confirm its efficacy as a medicinal agent.
3 citations
,
January 2019 in “Elsevier eBooks” This article discusses the importance of interpreting laboratory data and performing physical assessments to support pharmacists in clinical decision-making and patient consultations, but reports no new empirical findings.
January 2026 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study suggests that metformin's ability to enhance insulin sensitivity may improve acanthosis nigricans by addressing the underlying insulin resistance.
107 citations
,
September 2002 in “Journal of Investigative Dermatology” This study identified a distinct "exogen" phase in the hair cycle during which hair shedding occurs, primarily coupled with the anagen phase, rather than as part of the telogen phase.
30 citations
,
November 2008 in “Facial Plastic Surgery” This review discusses hair transplant techniques for female pattern hair loss and reports no new clinical results; it highlights the benefits of transplants combined with various treatments for improved hair density and styling options.
January 2024 in “Wiadomości Lekarskie” In this study, researchers developed a novel computational framework using deep reinforcement learning to identify strategies for cellular reprogramming in gene regulatory networks, showing its effectiveness in a model of immune response against infection.
Growing hair follicles from cultured cells could potentially treat baldness, but more research is needed.
4 citations
,
December 1985 in “Archives of Dermatological Research” Eye lens capsules are the best for growing human skin cells.
2 citations
,
October 2023 in “Animals” Lacto-fermentation changes amino acid profiles in bovine colostrum, but results are inconsistent.
31 citations
,
January 2021 in “Plants” This study found that light and sucrose have opposing effects on root length but collectively enhance root hair emergence and elongation in plant roots.