Hair Multiplication With Dermal Papilla-Like Tissue Containing Human Dermal Papilla Cells
June 2014
in “
Biotechnology and Bioprocess Engineering
”
hair multiplication dermal papilla tissue human dermal papilla cells alopecia bioartificial dermal papilla tissue dermal papilla-like tissues DPLTs cultured human dermal papilla cells DPCs hair-inducing ability in vivo hair sandwich model mouse scalp skin new hair growth injection site Outer Root Sheath Cells ORSCs in vitro hair development drug testing hair transplantation hair loss hair cell therapy hair growth hair transplant
TLDR Injecting lab-grown hair cells into the scalp can regrow hair.
The study investigated a novel hair cell therapy for alopecia using bioartificial dermal papilla tissue. Researchers created dermal papilla-like tissues (DPLTs) from cultured human dermal papilla cells (DPCs) and tested their hair-inducing ability in vivo with a modified hair sandwich model. Injecting DPLTs into mouse scalp skin led to new hair growth at the injection site within 2-3 weeks, with human cells from DPLTs and Outer Root Sheath Cells (ORSCs) present in the new hair. The results indicated that DPLTs could be useful for in vitro hair development studies, drug testing, and as an alternative for hair transplantation.
