August 2023 in “International Ayurvedic medical journal” This case study describes the successful treatment of a 7-year-old girl with alopecia areata using Ayurvedic approaches targeting skin and autoimmune issues, suggesting a potential alternative to long-term oral corticosteroids, which can cause undesirable side effects.
November 2022 in “Journal of Investigative Dermatology” This study found that short-term treatment with ROCKi significantly increased keratinocyte stem cell proliferation without affecting their stemness, suggesting a potential safe approach for improving in vitro keratinocyte cultures for clinical applications.
April 2012 in “Cancer Research” This study found that Stat3 influences the differentiation and migration of keratinocytes, potentially impacting epithelial carcinogenesis, by examining Stat3 activation or deletion effects in mouse models.
January 2012 in “DigtalCommons @ Texas Medical Center Library (Texas Medical Center)” This study found that Stat3 deletion in certain skin cells led to increased differentiation and altered stem cell behavior, suggesting its significant role in skin tumor development and keratinocyte migration.
April 2010 in “Cancer Research” This study found that altering CDK4 expression in mice affects the population of keratinocyte stem cells, suggesting a correlation with susceptibility to skin papillomas.
January 2007 in “The Year book of dermatology” Researchers successfully isolated and identified key stem cells in human hair follicles, which could help develop new skin and hair treatments.
This study found that a bio-based repair solution containing hydrolysed wool keratin, serine, and transglutaminase improved the physical and chemical properties of damaged hair, increasing its strength, flexibility, and thermal stability while offering long-lasting protection against chemical damage.
2 citations
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January 2024 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” This case report highlights that a 25-year-old female with Alopecia Areata showed significant hair regrowth on bald patches after three months of combined internal and external Ayurvedic treatments, offering a potential alternative to conventional treatments with minimal side-effects.
January 2025 in “Journal of Ayurveda and Integrated Medical Sciences” This review compiles references from classical Ayurveda texts on hair health, disorders, and treatments, emphasizing a holistic approach without reporting new clinical results.
February 2024 in “Journal of ayurveda and integrated medical sciences” This paper reviews Ayurvedic concepts related to PCOS and compares them with PCOS symptoms, without presenting new clinical findings.
January 2023 in “International Journal of Research in Medical Sciences & Technology” This article discusses the similarities between symptoms of systemic lupus erythematosus and the Ayurvedic condition pittaadhkiya vatarakta, and reports no new clinical results; the authors propose treating SLE with specific Panchkarma procedures.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that many participants with hair loss, or Khalitya, exhibited dietary incompatibilities and low calcium levels, aligning Ayurvedic concepts with modern dietary risk factors.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this observational study, researchers found that 55% of participants with hair loss known as Khalitya had serum calcium deficiency, which aligns with both Ayurvedic and modern perspectives linking poor nutrition to hair disorder, highlighting the importance of dietary regulation and stress management.
April 2012 in “Cancer research” In this study, the authors found that targeting mTORC1 with rapamycin inhibited TPA-induced skin tumor promotion by affecting keratinocyte proliferation, including critical stem cell populations in the mouse epidermis.
November 2006 in “評価・診断に関するシンポジウム講演論文集” This study found that KSR1 is essential for v-Ha-ras-mediated skin tumor formation in mice but not for MT-driven mammary tumor genesis, suggesting its potential as a therapeutic target in Ras/MAPK signaling.
20 citations
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April 2009 in “Cell Biology International” This study demonstrates that bulge KSCs from hair follicles can transdifferentiate into corneal epithelial-like cells under specific conditions, which could support bioengineered cornea development.
This study found that the novel bacteriophage Halo KS-7 shows strong antibacterial activity against carbapenem-resistant Klebsiella pneumoniae and significantly promotes wound healing in mice, making it a promising biocontrol agent for managing multidrug-resistant infections.
79 citations
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July 2022 in “Sensors” In this study, researchers evaluated various machine learning models for predicting type 2 diabetes risk, finding that Random Forest and K-NN models performed best in terms of precision, recall, accuracy, and other metrics using common symptoms as features.
12 citations
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November 2007 in “Journal of Investigative Dermatology” CD200 is not a reliable marker for identifying stem cells in all skin types.
January 2016 in “Hematology & Transfusion International Journal” This study reported that three months of platelet-rich plasma injections improved hair counts, thickness, root strength, and overall alopecia in patients with androgenic alopecia, with no major adverse effects.
May 2025 in “Clinical Medicine Insights Case Reports” This case study reported on a 6-year-old boy with Kindler Syndrome born to consanguineous parents, featuring atypical symptoms like hyperpigmented macules and glucose intolerance, contributing to expanding insights into the condition's phenotypic diversity.
November 2022 in “Journal of Investigative Dermatology” This study found that "early" transit amplifying cells, marked by CD271, are the first keratinocyte stem cell progenitors with distinct features, playing a significant role in early epidermal differentiation and regeneration.
5 citations
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October 2003 in “PubMed” This case report describes a 30-year-old male with a late diagnosis of Kallmann's syndrome, highlighting the necessity of hormonal therapy to reduce the risk of osteoporosis and bone fractures despite the patient's acceptance of his physical appearance.
October 2025 in “Journal of the Endocrine Society” This report highlights that Klinefelter syndrome is often underdiagnosed due to phenotypic variability and emphasizes the importance of thorough physical examinations to improve diagnostic timing.
February 2026 in “Frontiers in Medical Technology” This review discusses current knowledge of keratinocyte stem cell dynamics, including their regenerative roles and potential applications beyond wound healing, but presents no new clinical findings.
52 citations
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February 2003 in “Archives of dermatology” In this open-label trial, 9-cis-retinoic acid showed moderate activity against Kaposi sarcoma in AIDS patients, but its use is limited by substantial side effects at higher doses.
October 2023 in “Indian Journal of Ophthalmology - Case Reports” This report details the clinical presentation of an 18-year-old female with Kallmann syndrome, noting her ocular issues and differences in sexual development. The researchers treated her eye conditions cosmetically with superficial keratectomy and amniotic membrane graft, followed by corneal tattooing and strabismus correction.
6 citations
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February 1997 in “International Journal of Dermatology” In this study, the lack of cathepsin expression in Kaposi's sarcoma lesions suggests a benign hyperplastic origin for these lesions.
2 citations
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January 2008 in “International Journal of Neuroscience” This article presents a case of delayed diagnosis of Kearns-Sayre syndrome in a 38-year-old man and reviews clinical and laboratory findings associated with the disorder, reporting no new results.
April 2010 in “Cancer Research” In this study, Stat3 activation in transgenic mice led to a decrease in stem cells in the hair follicle bulge, suggesting its crucial role in epidermal growth and stem cell maintenance.